OKT With Gaze and Postural Stabilization on Vertigo, MS and QOL in VBH

NCT07575074 | Not Yet Recruiting

• 1 other identifier: REC/RCR & AHS/24/02100
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study will evaluate the effects of optokinetic training combined with postural stabilization and gaze stability exercises on motion sickness, balance, gaze stability, and quality of life in individuals with vestibular hypofunction.

Conditions

Vestibular Disorder

Keywords

Balance; gaze stability; motion sickness; optokinetic training

Outcome Measures

Primary Outcomes (4)

• Motion sickness susceptibility questionnaire

  The Motion Sickness Susceptibility Questionnaire (MSSQ) is a widely used tool that assesses an individual's predisposition to motion sickness in various environments, such as vehicles, amusement rides, and virtual reality.

  8th week

• Berg balance scale

  The Berg Balance Scale (BBS) is a reliable clinical tool used to assess balance in individuals, particularly older adults and those with balance impairments. It includes 14 tasks each scored from 0 (cannot perform) to 4 (performs independently). The BBS has a maximum score of 56, and most of the patients show a low fall risk of 41 to 56 scores, medium risk of 21 to 40 scores, and a high risk of 0 to 20 scores.

  8th week

• Dynamic visual acuity test for gaze stability

  The Dynamic Visual Acuity (DVA) Test is a widely used clinical test to assess gaze stability, particularly in individuals with vestibular dysfunction. It evaluates a person's ability to maintain clear vision during head movements, which requires stable gaze control. The test involves reading porotype letters or symbols displayed on a screen, first in a stationary position and then while moving the head horizontally and vertically at a standardized speed (usually around 2 Hz)

  8th week

• Head impulse test

  The Head Impulse Test (HIT) is a diagnostic tool used to evaluate the function of the vestibulo-ocular reflex (VOR), essential for maintaining gaze stability during rapid head movements. In this test, a clinician rapidly and unpredictably turns the patient's head to the left or right while the patient focuses on a stationary target, typically the clinician's nose. For a healthy VOR, the eyes should remain fixed on the target despite the head movement

  8th week

Study Arms (2)

Group A Habituation exercises

EXPERIMENTAL

Group A performed a regime of Habituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness

Other: Group A Habituation exercises

Group B Optokinetic training protocol

EXPERIMENTAL

Group B underwent a structured optokinetic training protocol combined with postural stabilization and gaze stability exercises, targeting both gaze and postural control systems.

Other: Group B Optokinetic training protocol

Interventions

Group A Habituation exercises OTHER

Habituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness (38). Each session, lasting approximately 20-25 minutes, involved exercises conducted for 20 minutes per day, five times a week. Each session, lasting approximately 30-45 minutes, included low-intensity breathing exercises aimed at promoting relaxation and moderate-intensity aerobic activities, such as walking or cycling, at 50-60% of the participant's maximum heart rate.

Group A Habituation exercises

Group B Optokinetic training protocol OTHER

10-minute warm-up, followed by 20-25 minutes of moderate-intensity optokinetic exercises (viewing controlled moving visual patterns), postural exercises involving controlled head and body movements to engage the vestibular system, and gaze stability exercises, which require focusing on a stationary target during head movements to improve the vestibulo-ocular reflex. The session concluded with a 10-15-minute cool-down to aid relaxation. These sessions continued for 12 weeks

Group B Optokinetic training protocol

Eligibility Criteria

• Age: 20 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Male and female patients age 20 and 40 years
• Passengers who have motion sickness during travelling
• Patients of vestibular migraine who experience motion sickness
• Participants experiencing vertigo, dizziness or imbalance related to vestibular hypofunction over the past three months

You may not qualify if:

• Patients who have seasickness and simulator sickness excluded.
• Patients having vestibular disease and chronic neurological disease.
• Participants who have completed formal vestibular rehabilitation in last 6 months excluded
• Patients with severe visual impairments and orthopedic conditions excluded.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Ittefaq Hospital Lahore

Lahore, Punjab Province, 54500, Pakistan

Location

MeSH Terms

Conditions

Vestibular Diseases; Motion Sickness

Condition Hierarchy (Ancestors)

Labyrinth Diseases; Ear Diseases; Otorhinolaryngologic Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Javeria Ghazal, MSNMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Muneeb Khan, PhD

CONTACT

923367993611; muneeb.khan@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 22, 2026
• First Posted: May 8, 2026
• Study Start (Estimated): May 15, 2026
• Primary Completion (Estimated): August 15, 2026
• Study Completion (Estimated): September 14, 2026
• Last Updated: May 8, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)