NCT07574398

Brief Summary

A single-center, large-sample, long-term longitudinal study was conducted to explore the trends and characteristics of changes in growth, development in pediatric liver transplant recipients, with the aim of guiding the development of intervention strategies and optimizing follow-up protocols.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
275

participants targeted

Target at P75+ for all trials

Timeline
44mo left

Started Nov 2024

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress29%
Nov 2024Dec 2029

Study Start

First participant enrolled

November 20, 2024

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

April 27, 2026

Completed
10 days until next milestone

First Posted

Study publicly available on registry

May 7, 2026

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2029

Last Updated

May 7, 2026

Status Verified

May 1, 2026

Enrollment Period

5.1 years

First QC Date

April 27, 2026

Last Update Submit

May 4, 2026

Conditions

Growth, Development in Pediatric Liver Transplant Recipients

Outcome Measures

Primary Outcomes (1)

  • BMI Z-score

    1 week before liver transplantation; 1 month, 3 months, 6 months, 1 year, 3 years, and 5 years after liver transplantation

Secondary Outcomes (1)

  • Overall survival

    1 week before liver transplantation; 1 month, 3 months, 6 months, 1 year, 3 years, and 5 years after liver transplantation

Eligibility Criteria

AgeUp to 1 Year
Sexall
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Children who underwent liver transplantation.

You may qualify if:

  • Children with end-stage liver disease of various etiologies requiring liver transplantation.
  • Approved by the ethics committee, and written informed consent has been obtained from the parents/legal guardians.
  • Age ≤ 1 year (infancy).

You may not qualify if:

  • Age older than 1 year old.
  • Accept liver kidney combined transplantation surgery or second liver transplantation surgery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China

RECRUITING

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 27, 2026

First Posted

May 7, 2026

Study Start

November 20, 2024

Primary Completion (Estimated)

December 31, 2029

Study Completion (Estimated)

December 31, 2029

Last Updated

May 7, 2026

Record last verified: 2026-05

Locations

CN(1)