3D-US Construct on Volumetric Assessment of Lung Disease & Clinical Application

NCT07574255 | Not Yet Recruiting

• 1 other identifier: 202604005DIND
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to establish the three-dimensional construct of lung lesion via ultrasound in patients with peripheral lung lesions or any superficial lesion in thoracic fields. The primary question our study aims to answer is: Whether the 3D ultrasound morphology can reflect lung disease entities? Whether the 3D volumetric follow-up protocol can be standardised to reflect lung disease status?

Conditions

Lung Ultrasound; Lung Cancer (Diagnosis); Peripheral Lung Lesions; Ultrasound Assessment

Keywords

lung ultrasound; three-dimensional ultrasound; peripheral lung lesions

Outcome Measures

Primary Outcomes (1)

• volume of measured lesion

  Standard volume will be defined by computed tomography measurement, and the ultrasound 3D-volmetric result would be compared

  from enrollment, every 6 weeks until 24th week

Study Arms (1)

ultrasound work-up

participants with peripheral lesions, not confined to lung, referred for ultrasound workup

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants with peripheral lung lesions or with lesions located at superficial thoracic field will be recruited from referral cases for ultrasound workup

You may qualify if:

• Participants suspect with lung lesions referred for ultrasound workup

You may not qualify if:

• Participants aged \< 18 years
• Participants refusal
• Participants with implanted metal in scanning area interfering data collection
• Participants who cannot perform breath holding for at least 1 second

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan

Location

MeSH Terms

Conditions

Lung Neoplasms; Disease

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• YEN-LIN CHEN, Doctor of Medicine

  National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

YEN-LIN CHEN, Doctor of Medicine

CONTACT

+886-2312-3456; moich.chen@gmail.com

YAO-WEN KUO, Ph.D

CONTACT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 3, 2026
• First Posted: May 7, 2026
• Study Start (Estimated): May 30, 2026
• Primary Completion (Estimated): February 28, 2031
• Study Completion (Estimated): February 28, 2031
• Last Updated: May 7, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)