Apple Vision Pro-Assisted Vascular Identification in Lung Surgery

NCT07573748 | Not Yet Recruiting

• 1 other identifier: HEYLL202654
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study is testing whether a new mixed-reality head-mounted display (Apple Vision Pro) can help surgeons see blood vessels more clearly during lung surgery. During the operation, doctors usually need to identify and protect important blood vessels to avoid bleeding. In this study, surgeons will wear the Apple Vision Pro device, which shows 3D images of the lungs and blood vessels. This may help them find vessels more accurately and make surgery safer. Participants scheduled for lung surgery at Huai'an Second People's Hospital will be invited to join. Before the operation, participants will have a CT scan. During surgery, doctors will use the device while performing the procedure. The study does not change the standard surgical steps, and there are no extra risks for participants. The main goal is to see if this new technology makes surgery easier and safer. Participation is voluntary, and all personal information will be kept confidential.

Conditions

Lung Neoplasms; Mixed Reality

Keywords

Lung Neoplasms; Mixed reality; Intraoperative Navigation; Three-Dimensional Imaging

Outcome Measures

Primary Outcomes (1)

• Accuracy of Perivascular Anatomical Identification

  The primary outcome is the accuracy of identifying critical perivascular anatomical structures (including pulmonary arteries, veins, and bronchi) using Apple Vision Pro. Accuracy will be measured by comparing the real-time navigation display with the actual anatomy confirmed by the surgeon during dissection. The primary endpoint is the successful identification of the correct transection plane that avoids injury to adjacent arteries, veins, or bronchi. Any discrepancy leading to potential mis-transection will be recorded.

  During the critical dissection and transection phase of lung surgery

Study Arms (1)

Experimental

EXPERIMENTAL

Participants in this arm will undergo lung surgery using Apple Vision Pro for intraoperative vascular navigation

Device: Apple Vision Pro

Interventions

Apple Vision Pro DEVICE

Use of Apple Vision Pro headset for augmented reality-assisted surgical navigation during lung surgery. The device will be worn by the surgeon to visualize critical anatomical structures and navigation pathways in real-time.

Experimental

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged 18 years or older. Diagnosed with lung nodules or early-stage lung cancer requiring surgical resection (lobectomy or segmentectomy).
• Scheduled for elective lung surgery at Huai'an Second People's Hospital. American Society of Anesthesiologists (ASA) Physical Status Classification I-III.
• Ability to understand and sign the informed consent form. Willingness to undergo surgery with the Apple Vision Pro navigation assistance.

You may not qualify if:

• Patients under 18 years of age. Pregnant or breastfeeding women. Patients with severe cardiopulmonary dysfunction (e.g., severe COPD, unstable angina, recent myocardial infarction) that would contraindicate surgery.
• Participation in another interventional clinical trial within the past 30 days. Inability to cooperate with the surgical team or follow study procedures.

Sponsors & Collaborators

• The Second People's Hospital of Huai'an: lead

Related Publications (4)

• Zhou AE, Klufas T, Feng H. Leveraging Apple Vision Pro for Dermatologic Surgery Education and Intraoperative Recording. Indian Dermatol Online J. 2026 Mar 1;17(2):294-295. doi: 10.4103/idoj.idoj_692_25. Epub 2025 Dec 12. No abstract available.

  PMID: 41403068 BACKGROUND

• Shen K, Li W, Xie Z. Preliminary application of Apple Vision Pro (AVP) in laparoscopic gastrointestinal surgery. Int J Surg. 2025 Nov 1;111(11):7898-7905. doi: 10.1097/JS9.0000000000003066. Epub 2025 Jul 17.

  PMID: 40679982 BACKGROUND

• Li C. Apple Vision Pro as an augmentative tool in surgery: a double-edged scalpel. Ann Med Surg (Lond). 2024 Oct 11;86(11):6407-6408. doi: 10.1097/MS9.0000000000002645. eCollection 2024 Nov. No abstract available.

  PMID: 39525735 BACKGROUND

• Shanbhag NM, Bin Sumaida A, Al Shamisi K, Balaraj K. Apple Vision Pro: A Paradigm Shift in Medical Technology. Cureus. 2024 Sep 17;16(9):e69608. doi: 10.7759/cureus.69608. eCollection 2024 Sep.

  PMID: 39308843 BACKGROUND

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Chuxu Wang, Attending Physician

  The Second People's Hospital of Huai'an

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Chuxu Wang, Attending Physician

CONTACT

+86 15996195616; wangchuxu@qq.com

Bo Min, Associate Professor

CONTACT

+86 18851392328; doctor_min@163.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: This is a single-arm, prospective study. All participants will undergo standard-of-care lung surgery with the addition of the Apple Vision Pro mixed-reality headset for intraoperative vascular navigation. There is no control group.

Study Record Dates

• First Submitted: April 24, 2026
• First Posted: May 7, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: May 7, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share