Myocardial Function Recovery Prediction Post Primary PCI Using the Estimate of Myocardial Salvage in Gated SPECT Early After Acute Myocardial Infarction

NCT07568587 | Completed DMC

• 1 other identifier: D 308
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Our aim was to correlate functional and perfusion abnormalities early post primary percutaneous coronary intervention after acute myocardial infarction in ST elevation myocardial infarction patients to estimate myocardial salvage, and to predict left ventricular ejection fraction (LVEF) recovery and remodeling in gated SPECT at follow-up.

Conditions

ST Elevation Acute Myocardial Infarction

Outcome Measures

Primary Outcomes (1)

• Myocardial Salvage assessed by an early gated SPECT Myocardial Perfusion Image study can predict LVEF evolution after primary PCI for Acute Myocardial Infarction.

  6 months

Study Arms (1)

ST Elevation Myocardial Infarction patients

Primary PCI

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population is a consecutive cohort of patients post primary PCI at Kasr Al-Aini Cardiac Centre, Cairo University.

You may qualify if:

• STEMI patients underwent primary PCI.

You may not qualify if:

• Patients who were lost to follow-up at 6 months post index-SPECT MPI study.
• Patients subsequently underwent a coronary revascularization procedure \[percutaneous coronary intervention (PCI) or coronary bypass surgery (CABG)\] within 60 days post index-SPECT MPI post PCI.
• Patients had a documented history of prior MI or coronary revascularization
• Patients with severe valvular disease and/or non-ischemic cardiomyopathy.
• Patients with renal and/or hepatic critical illness.

Sponsors & Collaborators

• Fayoum University: lead

Study Sites (1)

Faculty of Medicine

Al Fayyum, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer of Critical Care Medicine

Study Record Dates

• First Submitted: April 21, 2026
• First Posted: May 6, 2026
• Study Start: October 9, 2021
• Primary Completion: April 21, 2026
• Study Completion: April 21, 2026
• Last Updated: May 6, 2026

Record last verified: 2021-10

Locations

EG (1)