Infiltration Pattern of Locally Advanced ESCC

NCT07567716 | Enrolling By Invitation

• 1 other identifier: IS25220
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Prospectively collect the pathological records of ESCC patients, and analyse the infiltration pattern of ESCC.

Conditions

Esophageal Squamous Cell Carcinoma (ESCC); Infiltration; Tumour

Keywords

esophageal squamous cell carcinoma; infiltration pattern; prognosis; resection margin

Outcome Measures

Primary Outcomes (1)

• Infiltration pattern

  Direct infiltration length of ESCC beyond macroscopic margin and multiple lesions of ESCC.

  Postoperatively, based on the pathological results of the specimen. Usually, the results will be reported within one month after surgery.

Study Arms (1)

esophagectomy group

Receive esophagectomy for treatment

Other: Esophagectomy; Procedure: Esophagectomy

Interventions

Esophagectomy OTHER

Esophagectomy by McKeown method

esophagectomy group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with c/ycT2-3 esophageal squamous cell carcinoma (ESCC) who underwent McKeown esophagectomy.

You may qualify if:

• cervical or thoracic ESCC
• received esophagectomy
• preoperative stage T2-3
• no viable multiple lesions
• received McKeown esophagectomy

You may not qualify if:

• Incomplete clinical materials

Sponsors & Collaborators

• Shanghai Chest Hospital: lead

Study Sites (1)

Shanghai Chest Hospital

Shanghai, 20030, China

Location

Related Publications (1)

• MA G W, RONG T H, WU Q L, et al. Giant pathologic section in the study of optimal length of surgical resection for esophageal carcinoma [J]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2003, 25(5): 472-474.

  BACKGROUND

MeSH Terms

Conditions

Esophageal Squamous Cell Carcinoma; Neoplasms; Margins of Excision

Interventions

Esophagectomy

Condition Hierarchy (Ancestors)

Carcinoma, Squamous Cell; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms, Squamous Cell; Esophageal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Head and Neck Neoplasms; Digestive System Diseases; Esophageal Diseases; Gastrointestinal Diseases; Morphological and Microscopic Findings; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Digestive System Surgical Procedures; Surgical Procedures, Operative

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof.

Study Record Dates

• First Submitted: April 22, 2026
• First Posted: May 5, 2026
• Study Start: October 1, 2025
• Primary Completion: April 1, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: May 5, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)