A Prospective Analysis of Thulium Fiber Laser Efficiency
1 other identifier
interventional
61
1 country
1
Brief Summary
Patients diagnosed with urolithiasis will be prospectively enrolled in this study. Preoperative diagnostic assessment will be performed using computed tomography (CT). Key parameters, including stone dimensions, quantity, total stone burden, and stone density (Hounsfield units), will be evaluated preoperatively. This study aims to analyze data from patients who undergo ureteroscopic Thulium Fiber Laser (TFL) lithotripsy and achieve a stone-free status within a single procedural session. Based on these data, a 'Specific Energy Coefficient' will be derived to enable the preoperative prediction of the total laser energy required for successful lithotripsy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jun 2025
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
January 31, 2026
CompletedFirst Submitted
Initial submission to the registry
April 28, 2026
CompletedFirst Posted
Study publicly available on registry
May 5, 2026
CompletedMay 8, 2026
May 1, 2026
8 months
April 28, 2026
May 5, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
thulium fiber laser energy consumption per mm3xHu
4 weeks
Study Arms (1)
Stone-free
EXPERIMENTALInterventions
Procedures were performed by two high-volume experienced endourologists. Semirigid URS (7.5-9.5 F) was utilized for ureteral stones, while flexible URS (7.5 F) with a ureteral access sheath (10/12 F or 12/14 F) was preferred for renal stones. A 200 µm Thulium fiber was employed in all cases. Fragmentation was performed in Dusting Mode (Pulse Energy: 0.1-0.2 J, Frequency: 80-150 Hz).
Eligibility Criteria
You may qualify if:
- aged 18 years and above
- diagnosed with symptomatic urinary system stones
- planned URS or fURS
- normal upper urinary tract anatomy
- achieved stone-free
You may not qualify if:
- active urinary tract infection
- history of surgery/DJ stent placement within the last six months
- congenital renal anomalies
- patients with residual fragments on postoperative evaluation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Bozok Universitylead
Study Sites (1)
Yozgat Bozok University Faculty of Medicine
Yozgat, Yozgat, 66100, Turkey (Türkiye)
Related Publications (1)
Selmi V, Oztekin U, Caniklioglu M, Isikay L. Prediction of The Energy Required for Ho:YAG Laser Lithotripsy of Urinary Stones. Urol J. 2021 Apr 28;18(3):284-288. doi: 10.22037/uj.v18i.6442.
PMID: 33931845BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
volkan selmi
Yozgat Bozok University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
April 28, 2026
First Posted
May 5, 2026
Study Start
June 1, 2025
Primary Completion
January 31, 2026
Study Completion
January 31, 2026
Last Updated
May 8, 2026
Record last verified: 2026-05
Data Sharing
- IPD Sharing
- Will not share