Functional Limitations, Body Structure and Function Impairments, and Quality of Life in Adults After Surgical Treatment of Adolescent Idiopathic Scoliosis

NCT07559539 | Not Yet Recruiting

• 1 other identifier: SKE.0030.4.2026
• Study Type: observational
• Target: 90
• Locations: 0 countries
• Sites: N/A

Brief Summary

Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity, and a subset of patients undergo surgical correction during adolescence, most commonly posterior spinal fusion (PSF). Although surgical treatment improves deformity and quality of life in the short and mid-term, its long-term impact on functional status in adulthood remains insufficiently understood. This cross-sectional study aims to evaluate long-term outcomes in adults aged 25-40 years who underwent surgical treatment for AIS, compared with non-operated individuals with scoliosis and healthy controls. The study will assess limitations in daily functioning, musculoskeletal and respiratory function, pain, and compensatory mechanisms using standardized clinical measurements and questionnaires. The findings are expected to provide insight into long-term functional consequences of AIS and support the development of targeted physiotherapy and preventive strategies for adults treated for scoliosis during adolescence.

Conditions

Adolescence Idiopathic Scoliosis

Keywords

Adolescent Idiopathic Scoliosis; adult scoliosis; spinal fusion; Long-Term Adverse Effects

Outcome Measures

Primary Outcomes (1)

• ICF-Based Functional Limitations Questionnaire Total Score

  Author-developed questionnaire based on the International Classification of Functioning, Disability and Health (ICF), assessing body functions, activities, participation, and environmental factors. Higher total scores indicate greater disability.

  Baseline assessment, single study visit

Secondary Outcomes (7)

• SRS-22 Total Score

  Baseline assessment, single study visit

• Pain Intensity by Visual Analog Scale (VAS)

  Baseline assessment, single study visit

• Forced Vital Capacity (FVC % Predicted)

  Baseline assessment, single study visit

• Forced Expiratory Volume in 1 Second (FEV1 % Predicted)

  Baseline assessment, single study visit

• Angle of Trunk Rotation

  Baseline assessment, single study visit

Other Outcomes (6)

• Chest Expansion

  Baseline assessment, single study visit

• Cervical Rotation Range of Motion

  Baseline assessment, single study visit

• Peripheral Joint Range of Motion

  Baseline assessment, single study visit

Eligibility Criteria

• Age: 25 Years - 40 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Polish patients

You may qualify if:

• Female, age 25-40
• AIS diagnosed before age 18 (Cobb angle \>35°)
• Operated group: PSF, 10-25 years post-surgery
• Informed consent

You may not qualify if:

• Surgery other than PSF
• Surgery performed in adulthood

Sponsors & Collaborators

• Józef Piłsudski University of Physical Education: lead

MeSH Terms

Conditions

Scoliosis; Long Term Adverse Effects

Condition Hierarchy (Ancestors)

Spinal Curvatures; Spinal Diseases; Bone Diseases; Musculoskeletal Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 27, 2026
• First Posted: April 30, 2026
• Study Start (Estimated): May 16, 2026
• Primary Completion (Estimated): August 16, 2028
• Study Completion (Estimated): August 16, 2028
• Last Updated: April 30, 2026

Record last verified: 2026-03