BEYOND Study: Improving HIV Treatment and Well-Being Among Young MSM in Vietnam

NCT07559266 | Recruiting

• 2 other identifiers: CARMAHIN-US-380-7737
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The BEYOND Study aims to evaluate HIV treatment outcomes and well-being among young men who have sex with men (YMSM) living with HIV in Ho Chi Minh City, Vietnam. Despite progress in HIV services, YMSM continue to experience disparities in engagement in care, antiretroviral therapy (ART) adherence, and viral suppression, influenced by individual, social, and structural factors including stigma and limited access to person-centered care. This prospective cohort study will enroll 300 YMSM living with HIV from four clinical sites, including public, private, and community-based clinics. Participants will be followed for 12 months, with data collection at baseline, 6 months, and 12 months. The study will assess key outcomes including viral suppression, ART adherence, retention in care, mental health, and quality of life. In addition, in-depth interviews will be conducted with a subset of 20-30 participants to explore experiences with HIV care and barriers and facilitators to engagement. The study will also examine the implementation and perceived impact of person-centered care and one-stop-shop service models across different healthcare settings. Findings from this study will inform strategies to improve HIV treatment outcomes and support the development of integrated, patient-centered approaches to care for YMSM living with HIV in Vietnam and similar settings.

Conditions

HIV Infections; Mental Health; Medication Adherence

Keywords

HIV; YMSM; Antiretroviral Therapy Adherence; Viral Suppression; HIV Care Continuum; Retention in Care; Mental Health; Person-Centered Care; One-Stop-Shop Services; Integrated HIV Care; Ho Chi Minh City

Outcome Measures

Primary Outcomes (2)

• Viral Suppression Rate at 6 Months (HIV RNA <200 copies/mL)

  Proportion of participants achieving viral suppression, defined as HIV RNA \<200 copies/mL, based on clinical records. Participants lost to follow-up or with missing viral load data will be classified as not virally suppressed in the primary analysis

  6 months after enrollment

• Viral Suppression Rate at 12 Months (HIV RNA <200 copies/mL)

  Proportion of participants achieving viral suppression, defined as HIV RNA \<200 copies/mL, based on clinical records. Participants lost to follow up or with missing viral load data will be considered not virally suppressed in the primary analysis.

  12 months after enrollment

Secondary Outcomes (6)

• ART Adherence (≥95% of Prescribed Doses, 30-Day Recall)

  6 months and 12 months after enrollment

• Depressive Symptoms (Center for Epidemiologic Studies Depression Scale-Revised [CESD-R] Total Score)

  Baseline, 6 months, and 12 months

• Experience of Person-Centered HIV Care (Qualitative Assessment via In-Depth Interviews)

  At a single time point during the 12 month follow up

• Overall Depression Severity and Impairment (Overall Depression Severity and Impairment Scale [ODSIS] Total Score)

  Baseline, 6 months, and 12 months

• Anxiety Severity and Impairment (Overall Anxiety Severity and Impairment Scale [OASIS] Total Score)

  Baseline, 6 months, and 12 months

Study Arms (1)

Young MSM Living With HIV

Young men who have sex with men (YMSM) living with HIV enrolled from public, private, and community-based clinics in Ho Chi Minh City, Vietnam. Participants are followed prospectively for 12 months with assessments at baseline, 6 months, and 12 months to evaluate HIV treatment outcomes, including viral suppression, antiretroviral therapy adherence, retention in care, mental health, and quality of life.

Other: NO interventions listed

Interventions

NO interventions listed OTHER

NO interventions listed

Young MSM Living With HIV

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: male
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Young men who have sex with men (YMSM) aged 18-24 years living with HIV in Ho Chi Minh City, Vietnam, recruited from public, private, and community based clinics providing HIV care and related services.

You may qualify if:

• Aged 18 to 24 years
• Self-identified as male and reporting sex with men in the past 12 months
• Confirmed HIV diagnosis according to Vietnam Ministry of Health (MOH) national HIV testing guidelines
• Currently receiving antiretroviral therapy (ART) at one of the participating study clinics
• Residing in Ho Chi Minh City or nearby areas and able to attend study visits at participating clinics
• Able to understand and communicate in Vietnamese
• Willing and able to provide informed consent and participate in study procedures

You may not qualify if:

• Younger than 18 years or older than 24 years
• Not currently receiving ART or receiving ART from a non-participating clinic
• Severe cognitive impairment or mental health condition that, in the judgment of the research team, would interfere with the ability to provide informed consent or participation
• Currently enrolled in another clinical or behavioral study that may interfere with this study
• Unwilling or unable to provide informed consent or comply with study procedures

Sponsors & Collaborators

• Center for Applied Research on Men and Community Health, Vietnam: lead

Study Sites (1)

GoVap, MaiKhoi, Galant, Xomchieu

Ho Chi Minh City, Vietnam

RECRUITING

MeSH Terms

Conditions

HIV Infections; Psychological Well-Being; Medication Adherence

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Personal Satisfaction; Behavior; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior

Central Study Contacts

An Bao, Master of Public Health

CONTACT

0084913650536; baoan.lab@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 20, 2026
• First Posted: April 30, 2026
• Study Start: March 10, 2026
• Primary Completion (Estimated): May 30, 2027
• Study Completion (Estimated): December 31, 2027
• Last Updated: April 30, 2026

Record last verified: 2026-04

Locations

VN (1)