Comparative Effectiveness of Physiotherapeutic Scoliosis-Specific Exercises With Idiopathic Scoliosis

NCT07552662 | Completed DMC

• 1 other identifier: 825/2
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled trial evaluates the effectiveness of Physiotherapeutic Scoliosis-Specific Exercises (PSSE-Schroth) compared with General Exercises in adolescents with idiopathic scoliosis over a 12-month intervention period. Primary outcomes include Cobb angle progression and brace prescription rate. Secondary outcomes include trunk rotation, quality of life, self-image, and body symmetry.

Conditions

Scoliosis Idiopathic; Exercise; Scroth

Keywords

Scoliosis Idiopathic; Cobb angle; quality of life

Outcome Measures

Primary Outcomes (2)

• Change in Cobb Angle

  Cobb angle will be measured on standing anteroposterior spinal radiographs using the standard Cobb method. The angle is defined as the intersection of lines drawn parallel to the superior endplate of the upper-end vertebra and the inferior endplate of the lower-end vertebra of the primary curve. Measurements will be performed at baseline and after the intervention period, and the change in Cobb angle (in degrees) will be calculated. Lower values indicate an improvement in spinal curvature.

  Baseline to 12 Months

• Brace Prescription Rate

  The proportion of participants requiring orthotic bracing during the study period will be recorded. Brace prescription will be determined by a specialist according to established clinical criteria (e.g., curve magnitude, skeletal maturity, and risk of progression). The rate will be expressed as the percentage of participants prescribed a brace in each group during the follow-up period.

  12 Months

Secondary Outcomes (3)

• SRS-22 Questionnaire Score

  Baseline to 12 Months

• TAPS Score

  Baseline to 12 Months

• TRACE Score

  Baseline to 12 Months

Study Arms (2)

PSSE-Schroth Group

EXPERIMENTAL

Participants performed individualized PSSE-Schroth exercises based on curve pattern, including corrective breathing, postural correction, and ADL training.

Other: PSSE-Schroth Exercises

General Exercise Group

ACTIVE COMPARATOR

Participants performed general strengthening and stretching exercises without scoliosis-specific correction.

Other: General Exercises

Interventions

PSSE-Schroth Exercises OTHER

Participants performed individualized PSSE-Schroth exercises based on curve pattern, including corrective breathing, postural correction, and ADL training

PSSE-Schroth Group

General Exercises OTHER

Participants performed general strengthening and stretching exercises without scoliosis-specific correction.

General Exercise Group

Eligibility Criteria

• Age: 10 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Diagnosis of adolescent idiopathic scoliosis
• Cobb angle 10°-25°
• Risser sign 0-3 ATR \>5°
• Less than 1 year post-menarche (for females)

You may not qualify if:

• Previous brace treatment \* Non-idiopathic scoliosis
• Previous scoliosis surgery
• Neuromuscular or congenital scoliosis

Sponsors & Collaborators

• Hasan Kalyoncu University: lead

Study Sites (1)

Hasan Kalyoncu University

Gaziantep, Şahinbey, 27000, Turkey (Türkiye)

Location

Related Publications (8)

• Zhang Y, Chai T, Weng H, Liu Y. Pelvic rotation correction combined with Schroth exercises for pelvic and spinal deformities in mild adolescent idiopathic scoliosis: A randomized controlled trial. PLoS One. 2024 Jul 30;19(7):e0307955. doi: 10.1371/journal.pone.0307955. eCollection 2024.

  PMID: 39078854 RESULT

• Mohamed N, Acharya V, Schreiber S, Parent EC, Westover L. Effect of adding Schroth physiotherapeutic scoliosis specific exercises to standard care in adolescents with idiopathic scoliosis on posture assessed using surface topography: A secondary analysis of a Randomized Controlled Trial (RCT). PLoS One. 2024 Apr 30;19(4):e0302577. doi: 10.1371/journal.pone.0302577. eCollection 2024.

  PMID: 38687741 RESULT

• Kuru T, Yeldan I, Dereli EE, Ozdincler AR, Dikici F, Colak I. The efficacy of three-dimensional Schroth exercises in adolescent idiopathic scoliosis: a randomised controlled clinical trial. Clin Rehabil. 2016 Feb;30(2):181-90. doi: 10.1177/0269215515575745. Epub 2015 Mar 16.

  PMID: 25780260 RESULT

• Negrini S, Donzelli S, Aulisa AG, Czaprowski D, Schreiber S, de Mauroy JC, Diers H, Grivas TB, Knott P, Kotwicki T, Lebel A, Marti C, Maruyama T, O'Brien J, Price N, Parent E, Rigo M, Romano M, Stikeleather L, Wynne J, Zaina F. 2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth. Scoliosis Spinal Disord. 2018 Jan 10;13:3. doi: 10.1186/s13013-017-0145-8. eCollection 2018.

  PMID: 29435499 RESULT

• Weinstein SL, Dolan LA, Wright JG, Dobbs MB. Effects of bracing in adolescents with idiopathic scoliosis. N Engl J Med. 2013 Oct 17;369(16):1512-21. doi: 10.1056/NEJMoa1307337. Epub 2013 Sep 19.

  PMID: 24047455 RESULT

• Bago J, Sanchez-Raya J, Perez-Grueso FJ, Climent JM. The Trunk Appearance Perception Scale (TAPS): a new tool to evaluate subjective impression of trunk deformity in patients with idiopathic scoliosis. Scoliosis. 2010 Mar 25;5:6. doi: 10.1186/1748-7161-5-6.

  PMID: 20338048 RESULT

• Asher M, Min Lai S, Burton D, Manna B. The reliability and concurrent validity of the scoliosis research society-22 patient questionnaire for idiopathic scoliosis. Spine (Phila Pa 1976). 2003 Jan 1;28(1):63-9. doi: 10.1097/00007632-200301010-00015.

  PMID: 12544958 RESULT

• Langensiepen S, Semler O, Sobottke R, Fricke O, Franklin J, Schonau E, Eysel P. Measuring procedures to determine the Cobb angle in idiopathic scoliosis: a systematic review. Eur Spine J. 2013 Nov;22(11):2360-71. doi: 10.1007/s00586-013-2693-9. Epub 2013 Feb 27.

  PMID: 23443679 RESULT

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Outcome assessors and statisticians were blinded to group allocation. Participants and treating therapists were not blinded due to the nature of exercise interventions.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof.Dr.

Model Details: Participants were randomized in a 1:1 ratio to either PSSE-Schroth or General Exercise intervention.

Study Record Dates

• First Submitted: April 20, 2026
• First Posted: April 27, 2026
• Study Start: April 18, 2024
• Primary Completion: November 18, 2024
• Study Completion: November 18, 2025
• Last Updated: April 27, 2026

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)