Comparison of Patient Understanding and Anxiety According to the Delivery Method of Educational Videos

NCT07550686 | Recruiting DMC

• 1 other identifier: 9-2025-0190
• Study Type: interventional
• Target: 136
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate whether a generative artificial intelligence (AI)-based educational video is more effective than a conventional video in improving patient understanding and reducing anxiety before radiation therapy. In this prospective, randomized controlled study, participants will be assigned in a 1:1 ratio to either an AI-based avatar video group or a conventional video group consisting of PowerPoint slides with voice narration. Both videos will be standardized to have similar duration (approximately 5 minutes), identical key messages, and the same summary points. After providing informed consent, participants will complete questionnaires before and after watching the assigned video, as well as during the first week of treatment. Outcomes will include anxiety levels, knowledge comprehension, and satisfaction with the educational video. A total of 136 patients scheduled to undergo radiation therapy will be enrolled from two institutions. The findings of this study are expected to provide evidence on the effectiveness of AI-based educational tools in enhancing patient education and reducing pre-treatment anxiety.

Conditions

Radiotherapy; Patient Education

Keywords

Educational Video; Patient Education; Radiotherapy

Outcome Measures

Primary Outcomes (1)

• Anxiety score (APAIS)

  Anxiety will be measured using the Amsterdam Preoperative Anxiety and Information Scale (APAIS) (total score range: 6-30; higher scores indicate greater anxiety). Change from baseline will be analyzed using a linear mixed model.

  T1(Immediately after the intervention /during the pre-treatment consultation visit)

Secondary Outcomes (4)

• Anxiety level (K-HADS-A)

  T1(Immediately after the intervention (during the pre-treatment consultation visit)

• Anxiety level (APAIS, K-HADS-A)

  T2(During the first week of treatment)

• Knowledge score

  T1(Immediately after the intervention /during the pre-treatment consultation visit) and T2(during the first week of treatment)

• Satisfaction score

  T1(Immediately after the intervention /during the pre-treatment consultation visit) and T2(during the first week of treatment)

Study Arms (2)

AI-based Avatar Video

EXPERIMENTAL

Description: Participants will watch a generative AI-based educational video delivered through an avatar format. The video explains radiotherapy procedures, expected side effects, and self-care information. Duration is approximately 5 minutes. Intervention Type: Other Intervention Name: AI-based educational video Intervention Description: A standardized educational video generated using artificial intelligence avatar technology, designed to improve patient understanding and reduce anxiety prior to radiotherapy.

Other: AI-based educational video

PPT + Voice Narration Video

ACTIVE COMPARATOR

Description: Participants will watch a conventional educational video consisting of PowerPoint slides with voice narration. Content, duration (\~5 minutes), and key messages are equivalent to the experimental arm. Intervention Type: Other Intervention Name: Conventional educational video (PPT + narration) Intervention Description: A traditional educational video using slide-based presentation with voice narration covering radiotherapy-related information.

Other: Conventional educational video (PPT + narration)

Interventions

Conventional educational video (PPT + narration) OTHER

5-minute educational video using PowerPoint slides with voice narration covering identical content as the AI-based video, including radiotherapy procedures, side effects, and self-care information.

Also known as: Slide-based narrated video

PPT + Voice Narration Video

AI-based educational video OTHER

Standardized 5-minute educational video delivered via AI-generated avatar to explain radiotherapy procedures, expected side effects, and self-care information. Designed to improve patient understanding and reduce anxiety.

Also known as: Generative AI avatar video

AI-based Avatar Video

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 20 years
• Patients scheduled for radiotherapy
• Ability to watch video and comprehend audio, as assessed by the investigator
• ECOG performance status 0-1

You may not qualify if:

• Patients unable to complete questionnaires due to cognitive impairment or psychiatric disorders

Sponsors & Collaborators

• Yonsei University: lead
• Severance Hospital: collaborator

Study Sites (1)

Yongin Severance Hospital

Yongin-si, 365, South Korea

RECRUITING

Study Officials

• Hwakyung Byun, MD,PhD

  ongin Severance Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

HwaKyung Byun, MD, PhD

CONTACT

+82-31-5189-8166; hkbyun05@yuhs.ac

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: This is an open-label study in which participants and investigators are aware of the assigned intervention due to the nature of the educational video formats.
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Model Details: Participants are randomly assigned in a 1:1 ratio to receive either a generative AI-based avatar educational video or a conventional PowerPoint-based video with voice narration.

Study Record Dates

• First Submitted: April 10, 2026
• First Posted: April 24, 2026
• Study Start: December 1, 2025
• Primary Completion (Estimated): May 28, 2027
• Study Completion (Estimated): November 28, 2027
• Last Updated: April 29, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)