NCT07549971

Brief Summary

in 2015 a protocol for trail of labor after a single cesarean delivery was approved by medical committee of Pescara Hospital. A database from outpatient clinic evaluated all women after 34 weeks' gestation with a previous cesarean delivery. Patients with a specific medical indication for cesarean delivery were skipped, whilst the others were recruited within repetitive elective cesarean delivery or trial of labor based on maternal request. Patients were couselled on the opportunity of having a mechanical induction/ rupture of membranes and subsequent oxytocin infusion if needed due to prolonged gestation (above 41 weeks plus 3 days) or medical indication to delivery (i.e. gestational diabetes, hypertension, SGA, etc.)

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2015

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
11 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2025

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2026

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

April 17, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 24, 2026

Completed
Last Updated

April 24, 2026

Status Verified

April 1, 2026

Enrollment Period

11 years

First QC Date

April 17, 2026

Last Update Submit

April 17, 2026

Conditions

Trial of Labor; FailureTrial of Labor After Cesarean

Keywords

trial of labor after cesareanfailure of laborinduction of labor after cesarean

Outcome Measures

Primary Outcomes (2)

  • incidence of maternal request for trial of labor

    incidence of women with request of trial of labor through the time

    11 years

  • incidence of VBAC

    number of vaginal birth through the time

    11 years

Secondary Outcomes (2)

  • maternal adverse outcome

    11 years

  • neonatal adverse outcome

    11 years

Interventions

repetitive elective CDPROCEDURE

maternal and neonatal outcomes

Eligibility Criteria

Age18 Years - 57 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailspregnant women with a previous CD
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

All prengnat women attending labor ward of Santo Spirito Hospital of Pescara (Italy)

You may qualify if:

  • pregnant women
  • previous CD

You may not qualify if:

  • below 34 weeks' gestation
  • medical indication to CD

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Benetti CMS, Muhandule CJLS, Fogulin LB, Machado HDC, Amaral E. Cesarean delivery on maternal request and Robson classification. Int J Gynaecol Obstet. 2026 Feb 2. doi: 10.1002/ijgo.70841. Online ahead of print.

    PMID: 41626770RESULT

Study Officials

  • Claudio Celentano, MD

    University of Chieti Pescara School of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

April 17, 2026

First Posted

April 24, 2026

Study Start

January 1, 2015

Primary Completion

December 31, 2025

Study Completion

January 1, 2026

Last Updated

April 24, 2026

Record last verified: 2026-04