NCT07549178

Brief Summary

Providing care to individuals with serious mental illness can be challenging, requiring ongoing monitoring, treatment adjustments, and coordination of various medical and social services. Rates of emergency service and hospital use are high due to unexpected social, medical, and mental health crises. Stressors and poor adherence with treatment are common and can lead to rapid worsening in symptoms, job loss, homelessness, incarceration, or suicide. Clinician visits can be infrequent. Patient-clinician contact between visits is challenging and often nonexistent. As such, illness exacerbations usually occur with no clinician awareness in real time, leaving limited opportunity to provide services. Clinicians need interventions that are capable of monitoring and quickly detecting worsening behaviors and illness, to improve care coordination, outreach, and treatment. This project studies the effectiveness of enhanced care coordination using passive mobile data monitoring and support from peer specialists, with the goal of improving outcomes and reducing the need for acute care.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
46mo left

Started Aug 2026

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 17, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 23, 2026

Completed
3 months until next milestone

Study Start

First participant enrolled

August 3, 2026

Expected
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2029

6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2030

Last Updated

April 23, 2026

Status Verified

April 1, 2026

Enrollment Period

3.2 years

First QC Date

April 17, 2026

Last Update Submit

April 17, 2026

Conditions

Keywords

Mental Disorders, SevereVeteransRemote Sensing TechnologyMobile ApplicationsPatient Care TeamContinuity of Patient CareDisease ManagementPeer CoachingHealth Care Utilization

Outcome Measures

Primary Outcomes (1)

  • Acute care utilization

    Use of emergency service, use of hospitals, and death are each a binary measure (yes/no). These will be combined to make one binary measure that is yes if any one of these three is yes, and otherwise no.

    9 months

Secondary Outcomes (7)

  • Interpersonal supports - Interpersonal Support Evaluation List (ISEL)

    9 months

  • Patient activation - Patient Activation Measure (PAM)

    9 months

  • Engagement with care - Working Alliance Inventory (WAI)

    9 months

  • Receipt of care appropriate for chronic conditions - Patient Assessment of Chronic Illness Care (PACIC)

    9 months

  • Care experience - Ambulatory Care Experiences Survey (ACES)

    9 months

  • +2 more secondary outcomes

Study Arms (2)

CCM

ACTIVE COMPARATOR

Mobile monitoring, peer coaching, and enhanced care coordination

Behavioral: Care Coordination Mobile

Usual care

NO INTERVENTION

Usual care services

Interventions

Mobile monitoring, peer coaching, and enhanced care coordination

Also known as: CCM
CCM

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • a medical record diagnosis of Serious Mental Illness (SMI)
  • defined as schizophrenia, schizoaffective disorder, or bipolar disorder
  • receipt of care at the VA site during the prior 9 months
  • a Care Assessment Need (CAN) score over the 75th percentile, indicating high risk for hospitalization or death in the upcoming year
  • ownership of a smart phone

You may not qualify if:

  • none

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

VA Greater Los Angeles Healthcare System, West Los Angeles, CA

West Los Angeles, California, 90073-1003, United States

Location

Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

Philadelphia, Pennsylvania, 19104-4551, United States

Location

MeSH Terms

Conditions

Mental DisordersPatient Acceptance of Health Care

Condition Hierarchy (Ancestors)

Treatment Adherence and ComplianceHealth BehaviorBehavior

Study Officials

  • Alexander Stehle Young, MD MSHS

    VA Greater Los Angeles Healthcare System, West Los Angeles, CA

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ronald Calderon, MSW

CONTACT

Alexander S Young, MD MSHS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcomes assessors are not informed of the participant's participation in intervention or control
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: This project studies the effectiveness of an enhanced care coordination mobile intervention (CCM) that uses passive mobile data monitoring and support from peer coaches.
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 17, 2026

First Posted

April 23, 2026

Study Start (Estimated)

August 3, 2026

Primary Completion (Estimated)

October 31, 2029

Study Completion (Estimated)

April 30, 2030

Last Updated

April 23, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

A Limited Dataset (LDS) will be created and shared pursuant to a Data Use Agreement (DUA) appropriately limiting use of the dataset and prohibiting the recipient from identifying or re-identifying (or taking steps to identify or re-identify) any individual whose data are included in the dataset. Analytic datasets will be made available in accordance with local and national VA policy and compliance regulations. Mechanisms for sharing datasets will be based on infrastructure and resources available through either the local VA facility or VHA nationally. Researchers interested in accessing datasets will be required to sign a Data Use Agreement. Preservation and sharing of analytic datasets will allow other researchers to replicate published results and/or perform additional analyses. Researchers will be provided with a limited dataset as well as documentation regarding methods used for dataset creation and analytic procedures.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Final datasets will be stored on the local secure VA Research server for the period required by the VA Records Control Schedule. Analytic datasets will be made available in accordance with local and national VA policy and compliance regulations.
Access Criteria
Mechanisms for sharing datasets will be based on infrastructure and resources available through either the local VA facility or VHA nationally. Researchers interested in accessing datasets will be required to sign a Data Use Agreement.

Locations