Comparison of Transphyseal Screws and Eight Plates in Hemiepiphysiodesis for Coronal Knee Deformities: Short-Term Results

NCT07548749 | Not Yet Recruiting

• 1 other identifier: Soh-Med-26-3-3MS
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Coronal angular deformities of the lower limbs, such as bow legs and knock-knees, are frequently observed in childhood. While many cases are considered normal and resolve on their own, when these deformities become significant and progressive, they can disrupt the quality of life, leading to gait disturbances, pain, and in severe instances, joint instability. Additionally, these deformities may have indirect effects on other joints like the hip and ankle, and most importantly, they increase the risk of early osteoarthritis in the knee . It is generally accepted that a significant deformity that persists up to preadolescence will not correct spontaneously. Physiological alignment of the lower limb is crucial for the symmetrical distribution of weight over the surfaces of the joints, especially the knee. Indeed, severe coronal malalignment has been linked to knee pain, altered gait, and occasionally patellofemoral problems .

Conditions

Coronal Deformities Around the Knee

Outcome Measures

Primary Outcomes (1)

• correction of deformity

  6 months after surgery

Study Arms (2)

Go for transphyseal screws

ACTIVE COMPARATOR

Procedure: hemiepiphysiodesis

Go for eight plates

ACTIVE COMPARATOR

Procedure: hemiepiphysiodesis

Interventions

hemiepiphysiodesis PROCEDURE

Hemiepiphysiodesis is a safe, effective, and minimally invasive method for correcting angular deformities in growing children. The two main techniques-transphyseal screw and eight-plate-both rely on guided growth principles but differ in mechanics, control, and risk profile. Careful patient selection, timing, and follow-up are key to achieving optimal results.

Go for eight plates; Go for transphyseal screws

Eligibility Criteria

• Age: 3 Years - 14 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Both gender (males and females)
• Children ≥3 years old and growing children 2 years at least remaining in growth ( skeletal immature)
• Cases with progressive knee deformities around knee at any side.

You may not qualify if:

• \. Physeal closure.
• \. Physiological deformity in younger ages that could be managed conservatively ( age \< 3 years )
• \. Cases with metabolic or chronic illness conditions unresolved.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag faculty of medicine

Sohag, Egypt

Location

Central Study Contacts

Hossam Hosny omar Mansour

CONTACT

+201032366753; Hossamhosny00000@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Hossam hosny omar mansour

Study Record Dates

• First Submitted: April 15, 2026
• First Posted: April 23, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): April 1, 2027
• Last Updated: April 23, 2026

Record last verified: 2026-04

Locations

EG (1)