Physical Mobilisation to Acquired Brain Injury Patients in Intensive Care Units: a Prospective Cohort Study

NCT07548580 | Recruiting

• 1 other identifier: H-24084284
• Study Type: observational
• Target: 198
• Locations: 1 country
• Sites: 2

Brief Summary

The objective of this study is to quantify the amount of physical mobilisation provided to patients with moderate to severe acquired brain injury in Scandinavian neuro-ICs, and the association between intensity and duration of mobilisation, physiological data perceived to be related to the safety of high-level mobilisation, and amount of high-level mobilisation during the neuro-ICU stay.

Conditions

Acute Brain Injury

Keywords

Acute brain injury; Mobilisation

Outcome Measures

Primary Outcomes (3)

• Amount of physical mobilisation

  Amount of physical mobilisation provided during stay at neuro-ICU

  From admission at the intensive care unit (ICU) until discharge from the ICU, with a maximum of 3 months.

• Amount of high-level mobilisation

  Amount of high-level mobilisation during stay at neuro-ICU

  From admission at the intensive care unit (ICU) until discharge from the ICU, with a maximum of 3 months.

• Association between intensity and duration of mobilisation

  The association between the intensity and duration of mobilisation during stay at neuro-ICU

  From admission at the intensive care unit (ICU) until discharge from the ICU, with a maximum of 3 months.

Secondary Outcomes (1)

• Association between frequency of high-level mobilisation and outcomes indicated relevant

  From admission at the intensive care unit (ICU) until discharge from the ICU, with a maximum of 3 months.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adult patients admitted to a neuro-ICU or to a regular ICU due to moderate to severe traumatic brain injury or stroke.

You may qualify if:

• Adults (age ≥ 18 years)
• Admitted to a neuro-ICU or to a regular ICU with dedicated beds for severe acquired brain injury patients in Scandinavia
• Patients with moderate to severe traumatic brain injury (TBI) or stroke
• Patients must be intubated and expected to require mechanically ventilation for at least 24 hours.

You may not qualify if:

• Patients that are not likely to survive or for whom a decision has been made on palliative care.

Sponsors & Collaborators

• Rigshospitalet, Denmark: lead

Study Sites (2)

Rigshospitalet

Copenhagen, Denmark

RECRUITING

Odense Universitets Hospital

Odense, Denmark

ACTIVE NOT RECRUITING

MeSH Terms

Conditions

Brain Injuries

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Wounds and Injuries

Study Officials

• Christian Gunge Riberholt, PhD

  Rigshospitalet, Denmark

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Christian Gunge Riberholt, PhD

CONTACT

0045-38631600; christian.gunge.riberholt@regionh.dk

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior researcher PhD

Study Record Dates

• First Submitted: September 3, 2025
• First Posted: April 23, 2026
• Study Start: August 25, 2025
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: April 23, 2026

Record last verified: 2026-04

Locations

DK (2)