Effect of Kangaroo Mother Care on Energy Utilization in Preterm Neonates

NCT07548229 | Active Not Recruiting DMC

• 1 other identifier: medicine Ain Shams
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to assess the impact of kangaroo mother care on energy utilization in preterm neonates by measuring urinary levels of xanthine, uric acid, and malondialdehyde. It also aims to evaluate the effect of kangaroo mother care on physiological stress parameters in preterm neonates, as well as maternal emotional status

Conditions

Impact of Kangroo on Neonates

Keywords

kangroo; neonates

Outcome Measures

Primary Outcomes (5)

• Urinary biomarkers of energy utilization

  Urinary xanthine and uric acid levels measured using ELISA kits.

  3 hours before and 3 hours after intervention on day 3 of life

• Oxidative stress marker

  Urinary malondialdehyde level measured using ELISA kits.

  3 hours before and 3 hours after intervention on day 3 of life

• heart rate

  Heart rate measured using standard neonatal monitoring devices.

  Baseline and every 15 minutes during 1 hour intervention on day 3 of life

• Respiratory rate

  Respiratory rate measured using standard neonatal monitoring devices.

  Baseline and every 15 minutes during 1 hour intervention on day 3 of life

• temperature

  Body temperature measured using standard neonatal monitoring devices.

  Baseline and every 15 minutes during 1 hour intervention on day 3 of life

Secondary Outcomes (1)

• maternal emotional status

  : 3 hours before and 3 hours after intervention on day 3 of life

Study Arms (2)

study group

EXPERIMENTAL

babies at day 3 will have kangro mother care

Behavioral: kangroo mother care

control group

PLACEBO COMPARATOR

will have routine incubator care

Behavioral: routine incubation care

Interventions

kangroo mother care BEHAVIORAL

o All the preterm neonates will receive routine incubator neonatal care till day 3 of life. Then they will be subjected to the intervention according to the group; intervention group will undergo kangaroo mother care and control group without kangaroo mother care. o The neonates in the intervention group will be given 1 hour of kangaroo mother care by their own mothers once on day 3 of life after feeding. o The neonates in the control group will be given 1 hour of regular nursing care without kangaroo mother care once on day 3 of life after feeding.

study group

routine incubation care BEHAVIORAL

o All the preterm neonates will receive routine incubator neonatal care till day 3 of life. Then they will be subjected to the intervention according to the group; intervention group will undergo kangaroo mother care and control group without kangaroo mother care. o The neonates in the intervention group will be given 1 hour of kangaroo mother care by their own mothers once on day 3 of life after feeding. o The neonates in the control group will be given 1 hour of regular nursing care without kangaroo mother care once on day 3 of life after feeding.

control group

Eligibility Criteria

• Age: 1 Day - 1 Month
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Preterm neonates (32-36 weeks)
• Vitally stable
• On room air or low ventilatory support

You may not qualify if:

• Neonates requiring surgery
• Intraventricular hemorrhage
• Receiving sedatives (morphine, fentanyl, midazolam)
• Renal impairment
• Congenital anomalies
• Cyanotic heart disease
• Severe respiratory distress
• Hemodynamic instability
• Hypothermia
• Parental refusal

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams university

Cairo, Salam City, 14456, Egypt

Location

Related Publications (1)

• Morelius E, Ortenstrand A, Theodorsson E, Frostell A. Early maternal contact has an impact on preterm infants' brain systems that manage stress. Nursing children and young people. 2016; 28: 62-63.

  BACKGROUND

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assisstant prfessor

Study Record Dates

• First Submitted: January 16, 2026
• First Posted: April 23, 2026
• Study Start: May 15, 2025
• Primary Completion (Estimated): May 15, 2026
• Study Completion (Estimated): July 15, 2026
• Last Updated: April 27, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)