NCT07548216

Brief Summary

The goal of this clinical trial is to learn if osteopathic manipulative techniques add benefits for treatment of patients with progressive pulmonary fibrosis. The main questions it aims to answer are : Could osteopathic manipulative techniques add benefits for treatment of patients with progressive pulmonary fibrosis? Researchers will compare osteopathic manipulative techniques with chest physiotherapy to chest physiotherapy alone to see if osteopathic manipulative techniques works to treat progressive pulmonary fibrosis. Participants will: Take osteopathic manipulative techniques 2 days a week for 4 weeks and chest physiotherapy 3 days a week for 4 weeks

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
17mo left

Started May 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress1%
May 2026Oct 2027

First Submitted

Initial submission to the registry

April 14, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

April 23, 2026

Completed
8 days until next milestone

Study Start

First participant enrolled

May 1, 2026

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2027

Expected
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2027

Last Updated

April 23, 2026

Status Verified

April 1, 2026

Enrollment Period

1 year

First QC Date

April 14, 2026

Last Update Submit

April 21, 2026

Conditions

Outcome Measures

Primary Outcomes (3)

  • pulmonary function test - FVC

    FVC

    preintervention , post intervention after 4 weeks

  • pulmonary function test - FEV

    FEV

    pre intervention , post intervention after 4 weeks

  • pulmonary function test - FEV/FVC

    FEV/FVC

    pre intervention , post intervention after 4 weeks

Secondary Outcomes (2)

  • chest expansion measurment

    pre intervention , post intervention after 4 weeks

  • Modified Medical Research Council dyspnea scale

    pre intervention , post intervention after 4 weeks

Study Arms (2)

OMT and chest physiotherapy

ACTIVE COMPARATOR
Other: osteopathic manipulative techniques

conventional chest physiotherapy

ACTIVE COMPARATOR
Other: conventional chest physiotherapy

Interventions

for 4 weeks , 2 sessions per week

OMT and chest physiotherapy

for 4 weeks , 3 sessions per week

conventional chest physiotherapy

Eligibility Criteria

Age19 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Their age \> 18.
  • Both sexes.
  • Patients without excerbations.
  • FVC of the patient \<50% .
  • FEV1/ FVC of the patient \<50%.
  • Hemodynamic stable.
  • Conscious and cooperative.
  • Are able to participate in training actively.

You may not qualify if:

  • Patients with acute excerbations.
  • Acute or Uncontrolled Infections.
  • Active Malignancy.
  • Chest deformity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital of Beni Suef University

Banī Suwayf, Egypt

Location

Study Officials

  • Tamer I Abo elyazed, professor

    Beni-Suef University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Tamer I Abo elyazed, professor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
physical therapist

Study Record Dates

First Submitted

April 14, 2026

First Posted

April 23, 2026

Study Start

May 1, 2026

Primary Completion (Estimated)

May 1, 2027

Study Completion (Estimated)

October 1, 2027

Last Updated

April 23, 2026

Record last verified: 2026-04

Locations