Mobilizing Community Hypertension Access Pilot

NCT07547345 | Recruiting

• 1 other identifier: 25061903-IRB01
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted community settings on the West and South Sides of Chicago. Adults with uncontrolled hypertension will be identified and enrolled through community-based organizations, where a mobile clinical team-including community health workers, a pharmacist, and a registered nurse-will provide blood pressure screening, medication management, health education, and care coordination over a 3-month period. The study will assess participant engagement and acceptability, changes in systolic blood pressure. This pilot aims to address disparities in hypertension control by improving access to care in underserved communities and informing scalable, community-based models of chronic disease management.

Conditions

Hypertension

Keywords

Hypertension; Blood Pressure Control; Cardiovascular Disease Prevention; Pharmacist-Led Care; Community-Based Intervention; Community Health Workers; Mobile Health Services; Medication Management; Medication Adherence; Health Disparities; Underserved Populations; Social Determinants of Health; Care Coordination; Chronic Disease Management; Preventive Cardiology; Urban Health; Feasibility Study; Pilot Study; Cost-Effectiveness; Population Health

Outcome Measures

Primary Outcomes (1)

• Change in Systolic Blood Pressure (SBP)

  Mean change in systolic blood pressure from baseline to 12-week follow-up among participants enrolled in the LHC intervention.

  Baseline to 3 months (12 weeks)

Secondary Outcomes (9)

• SBP Reduction ≥10 mmHg

  12 weeks

• Blood Pressure Control

  12 weeks

• Medication Adherence

  Baseline and 12 weeks

• Feasibility (Recruitment and Retention)

  Through 12 weeks

• Acceptability of Intervention

  12 weeks

Study Arms (1)

Live Healthy Chicago Intervention

EXPERIMENTAL

Participants receive a 12-week community-based hypertension management intervention delivered by a mobile clinical team including community health workers, registered nurses, and pharmacists. The intervention includes blood pressure monitoring, medication management under a collaborative practice agreement with a physician, health education, social needs screening, and care coordination.

Behavioral: Community-Based Multidisciplinary Hypertension Management Program

Interventions

Community-Based Multidisciplinary Hypertension Management Program BEHAVIORAL

A 12-week community-based hypertension management intervention delivered in community settings. The program includes pharmacist-led medication management under collaborative practice agreement, RN-led clinical monitoring and follow-up, and CHW-led outreach, education, and care navigation. Participants receive blood pressure screening, medication titration when indicated, home blood pressure monitoring support, and linkage to primary care and social services.

Live Healthy Chicago Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults 18 years or older
• Record of two blood pressure readings of SBP\>130 on two separate occasions (days) within the past 3 months

You may not qualify if:

• Person is receiving dialysis
• Person has had a heart or kidney transplant
• Person is pregnant

Sponsors & Collaborators

• Rush University Medical Center: lead

Study Sites (1)

Rush University Medical Center

Chicago, Illinois, 60612, United States

RECRUITING

Related Publications (16)

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  PMID: 30354579 BACKGROUND

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  PMID: 24030130 BACKGROUND

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  PMID: 32495306 BACKGROUND

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MeSH Terms

Conditions

Hypertension; Medication Adherence

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Officials

• Elizabeth Lynch, PhD

  Rush University Medical Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Elizabeth Lynch, PhD

CONTACT

312-563-2254; Elizabeth_Lynch@rush.edu

Rebecca Dawar, MPH

CONTACT

312-942-8571; Rebecca_Dawar@rush.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor, Department of Family and Preventive Medicine

Study Record Dates

• First Submitted: April 1, 2026
• First Posted: April 23, 2026
• Study Start: February 20, 2026
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): March 1, 2027
• Last Updated: April 23, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)