NCT07546461

Brief Summary

This study evaluates the operational, environmental, and habitation-system requirements for sustained human presence on the lunar surface, the performance of the Lunar Gateway as a transit and staging architecture, and the pathways required to accelerate readiness for Martian surface habitation. The protocol examines habitat resilience, radiation exposure modeling, life-support continuity, EVA logistics, behavioral health in isolated environments, and systems-engineering workflows across lunar, transit, and Mars-analog environments. Special emphasis is placed on the identification, extraction, processing, and utilization of lunar water-ice deposits as a critical resource for life-support, radiation shielding, and in-situ propellant production. Findings will inform future mission design, habitation module development, and interplanetary operational frameworks.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
37mo left

Started May 2026

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress1%
May 2026Apr 2029

First Submitted

Initial submission to the registry

April 11, 2026

Completed
11 days until next milestone

First Posted

Study publicly available on registry

April 22, 2026

Completed
9 days until next milestone

Study Start

First participant enrolled

May 1, 2026

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2029

Last Updated

April 22, 2026

Status Verified

April 1, 2026

Enrollment Period

3 years

First QC Date

April 11, 2026

Last Update Submit

April 16, 2026

Conditions

Keywords

Lunar HabitationLunar Water-Ice ExtractionWater-Ice Thermal StabilityISRU Propellant ProductionLunar GatewayMars Transit ArchitectureMartian Surface HabitationHabitat Systems EngineeringECLSS ResilienceRadiation ShieldingEVA LogisticsDust MitigationInterplanetary Mission ArchitectureResource-Supported HabitationIn-Situ Oxygen and Hydrogen Production

Outcome Measures

Primary Outcomes (3)

  • Habitat System Resilience Index (HSRI)

    HSRI is a composite scale (0-100) assessing environmental stability, ECLSS uptime (%), redundancy activation success rate (%), and mean time to recovery (hours). Higher scores indicate better habitat resilience.

    36 months

  • Water-Ice Utilization Efficiency Ratio

    Efficiency ratio (%) measured using the Water-Ice Processing Performance Scale (WIPPS; 0-100%), quantifying the proportion of extracted ice converted into usable water, oxygen, hydrogen, and propellant. Higher values indicate greater efficiency.

    36 months

  • Radiation Modeling Accuracy Score

    Accuracy score (%) comparing predicted radiation dose (mSv) to measured dose using the Habitat Radiation Monitoring System (HRMS). Higher scores indicate greater predictive accuracy.

    36 months

Secondary Outcomes (12)

  • EVA Task Completion Time

    36 months

  • EVA Mobility Constraint Score

    36 months

  • Dust Intrusion Index

    36 months

  • Life-Support Continuity Score (LSCS)

    36 months

  • Behavioral Health Stability Index (BHSI)

    36 months

  • +7 more secondary outcomes

Study Arms (3)

Lunar Surface Habitation Cohort

Participants assigned to evaluate lunar surface habitation systems, including habitat stability, ECLSS performance, radiation shielding, EVA logistics, and water-ice extraction workflows.

Other: Habitat Systems EvaluationOther: Water-Ice Resource Utilization AssessmentOther: EVA and Mobility Operations

Lunar Gateway Transit Cohort

Participants assigned to assess Lunar Gateway transit operations, including docking workflows, resource transfer, life-support continuity, and staging of water-ice-derived consumables.

Other: Habitat Systems EvaluationOther: Water-Ice Resource Utilization Assessment

Martian Surface Analog Cohort

Participants assigned to operate within Mars-analog habitats to evaluate long-duration isolation, dust mitigation, power redundancy, and utilization pathways for Martian subsurface ice.

Other: Habitat Systems EvaluationOther: Water-Ice Resource Utilization AssessmentOther: EVA and Mobility Operations

Interventions

Operational assessment of habitat modules, environmental stability, ECLSS resilience, redundancy models, and failure-mode responses across lunar, transit, and Mars-analog environments.

Lunar Gateway Transit CohortLunar Surface Habitation CohortMartian Surface Analog Cohort

Evaluation of water-ice identification, extraction, thermal stability, processing, and conversion into potable water, oxygen, hydrogen, and in-situ propellant.

Lunar Gateway Transit CohortLunar Surface Habitation CohortMartian Surface Analog Cohort

Testing of EVA logistics, mobility constraints, dust mitigation strategies, and operational workflows in lunar and Mars-analog environments.

Lunar Surface Habitation CohortMartian Surface Analog Cohort

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants include adult analog crew members, habitat systems engineers, environmental control specialists, and mission operations personnel engaged in lunar surface, Lunar Gateway, and Mars-analog habitation assessments.

You may qualify if:

  • Adults aged 18-65
  • Able to participate in isolated, confined, or controlled operational environments
  • Prior experience in engineering, environmental systems, analog missions, or mission operations
  • Ability to perform EVA-analog tasks and operational workflows
  • Willingness to participate in multi-phase lunar, transit, and Mars-analog simulations

You may not qualify if:

  • Medical or physical limitations that prevent participation in isolated or operational environments
  • Conditions that limit safe participation in EVA-analog tasks
  • Inability to comply with operational protocols or safety requirements
  • Participation in conflicting operational studies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Truway Health, Inc. New York Headquarters

New York, New York, 10016, United States

Location

Related Publications (1)

  • Mkaouer B, Jemni M, Amara S, Chaabene H, Tabka Z. Kinematic and kinetic analysis of two gymnastics acrobatic series to performing the backward stretched somersault. J Hum Kinet. 2013 Jul 5;37:17-26. doi: 10.2478/hukin-2013-0021. eCollection 2013.

    PMID: 24146701BACKGROUND

Related Links

MeSH Terms

Interventions

Extravehicular Activity

Intervention Hierarchy (Ancestors)

Space FlightAviationTransportationTechnology, Industry, and Agriculture

Study Officials

  • Gavin C Solomon, President/CEO

    Truway Health, Inc.

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gavin C Solomon, President/CEO

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 11, 2026

First Posted

April 22, 2026

Study Start

May 1, 2026

Primary Completion (Estimated)

April 30, 2029

Study Completion (Estimated)

April 30, 2029

Last Updated

April 22, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

This study conducts a multiphase operational assessment of habitation systems across lunar surface, Lunar Gateway, and Mars-analog environments. It evaluates habitat resilience, life-support continuity, radiation exposure modeling, EVA logistics, and long-duration behavioral stability. A central focus is the identification, extraction, processing, and utilization of lunar and Martian water-ice resources to support life-support functions, radiation shielding, and in-situ propellant production. Findings will inform future mission architectures and accelerate readiness for sustained human habitation beyond Earth orbit.

Locations