Effects of Circuit Training on Cardiopulmonary Fitness in Multi Drug Abusers

NCT07546422 | Completed DMC

• 1 other identifier: Iftikhar Ahmad
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this research is to evaluate the effects of circuit training on cardiopulmonary fitness among the different categories of drug abusers. Randomized clinical trial is conducted in registered Drug Rehabilitation Center with Social Welfare Department of Khyber Pakhtunkhwa, Da Haq Awaz (Anti-Drugs Organization), Peshawar. The sample size is 60 participants (n=60). These participants were divided into two groups: Group A (n = 30) and Group B (n = 30). Study duration is of 6 months. Sampling technique applied was Non probability Purposive Sampling technique. Only male participants were included which age was 18-60 years with multi-drugs abusing. Tools used in the study are 6 Minute Walk Test, Step Test-VO2max, Spirometer Testing and Mini-Mental State Examination. Data was analyzed through SPSS 23.

Conditions

Drug Use and Addiction

Keywords

Circuit Training; Cardiopulmonary Fitness; Multi Drug Abusers.

Outcome Measures

Primary Outcomes (3)

• 6 Minute Walk Test for Distance

  The 6-minute walk test (6MWT) is a simple field test used to measure the distance an individual can walk on a flat, hard surface within six minutes. It is commonly used to evaluate functional exercise capacity and endurance, especially in populations with cardiopulmonary limitations. The test is performed in a straight corridor or walkway, and the total distance covered in six minutes is recorded

  4 Weeks

• Step Test-VO2max

  (Maximal Oxygen Uptake) the step test is used to assess cardiopulmonary fitness by evaluating heart and lung efficiency during exercise and recovery. The test requires a 12-inch step/platform, a stopwatch, and optionally, a metronome and heart rate monitor. After a 5-10 minute warm-up, the participant steps up and down at a rate of 96 beats per minute for 3 minutes. Immediately after, the participant sits down, and their heart rate is measured for 1 full minute to determine cardiovascular endurance and recovery rate.

  4 Weeks

• Mini-Mental State Examination (MMSE)

  (MMSE) is primarily used to assess cognitive function in the context of drug abusers, it can be relevant to evaluate cognitive impairment that may affect their ability to engage in and benefit from cardiopulmonary fitness programs. The MMSE evaluates cognitive domains such as orientation, memory, attention, language, and visuospatial skills. In drug abusers, cognitive deficits can influence their adherence to and effectiveness of cardiopulmonary interventions.

  4 Weeks

Secondary Outcomes (3)

• Forced Vital Capacity (FVC)

  4 weeks

• Forced Expiratory Volume in 1 second (FEV1)

  4 weeks

• Peak Expiratory Flow (PEF)

  4 weeks

Study Arms (2)

Group A

EXPERIMENTAL

The 4 weeks Circuit Training program, it will be of 3 times per week. Each CT workout includes 6 stations per Circuit Training. Before the training period, all participants underwent an exercise familiarization session to ensure proper execution of technique. The CT exercises includes five times of high knee, three minute stair climbing, five repetitions of pushups, 10 time sit ups/crunches, right and left single leg stands for long time as they continued balance and 10 times squad thrusts among the 6 stations.

Other: Circuit Training Program

Group B

OTHER

The Control Group will also receive the 4 weeks treatment program in which participants will receive educational sessions and lifestyle advice related to health and fitness but do not engage in a structured exercise program but will do just the traditional exercise such as walking.

Other: Conventional Training Program

Interventions

Circuit Training Program OTHER

FREQUENCY: 3 sessions per week for 4 weeks (total 12 sessions) INTENSITY: Moderate to high intensity. Exercises involved (e.g., pushups, high knees, stair climbing) TIME: 45-60 minutes per session Each session includes 6 stations, with repetitions (e.g., 10 sit-ups, 10 squats/burpees, 3 min stair climbing) TYPE: High knees (x5), 3-minute stair climbing, 5 push-ups, Sit-ups/crunches (x10),Single-leg stands (right and left), Squad thrusts/burpees (x10)

Group A

Conventional Training Program OTHER

FREQUENCY: 3 sessions per week for 4 weeks (total 12 sessions) INTENSITY: Low to moderate intensity Mostly educational and traditional walking-based TIME: 40-50 minutes per session Includes lifestyle modification sessions + physical activity (walking) TYPE: Conventional Training Program: Educational sessions, Health and lifestyle modification, Light aerobic activity (e.g., Traditional walking)

Group B

Eligibility Criteria

• Age: 18 Years - 60 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Participants meeting the below criteria, shall be recruited in the study:
• Those patients will be included who have completed acute detoxification period (15 days of Date of Admission) also the patients who were relapsed after 3 months of treatment and re-admitted.
• Only male participants will be included.
• Age of the participants will be 18 to 60 years old.
• Informed Consent will be taken from subjects or their legal guardians.
• Those participants will be included in the study that has complete relevant medical record (Multi Drug kit Report).
• Elderly drug abusers (Can perform 6 Minute Walk Test without complication)

You may not qualify if:

• Following participants will be excluded from the study:
• Glaucoma disease or severe mental illness, or a history of epilepsy/seizures.
• Serious systemic disease in the past three months, such as gastrointestinal bleeding, diabetes and hypertension.
• Diagnosed cardiopulmonary disease
• Any neurological complication
• Those patients who having Hepatitis C Virus, HIV \& Hepatitis B Virus will be excluded.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Da Haq Awaz, Anti-drug Organization

Peshawar, Pakistan

Location

Related Publications (5)

• Song L-y, Huang Z-j, Yang S-s, Bu D-r, Yi N, Zheng X. Effectiveness of short-term exercise on drug rehabilitation effect for drug abusers: A systematic review and meta-analysis. International Journal of Sport and Exercise Psychology. 2023:1-26

  BACKGROUND

• Ramos-Campo DJ, Andreu Caravaca L, Martinez-Rodriguez A, Rubio-Arias JA. Effects of Resistance Circuit-Based Training on Body Composition, Strength and Cardiorespiratory Fitness: A Systematic Review and Meta-Analysis. Biology (Basel). 2021 Apr 28;10(5):377. doi: 10.3390/biology10050377.

  PMID: 33924785 BACKGROUND

• Getty AK, Wisdo TR, Chavis LN, Derella CC, McLaughlin KC, Perez AN, DiCiurcio WT 3rd, Corbin M, Feairheller DL. Effects of circuit exercise training on vascular health and blood pressure. Prev Med Rep. 2018 Feb 27;10:106-112. doi: 10.1016/j.pmedr.2018.02.010. eCollection 2018 Jun.

  PMID: 29850395 BACKGROUND

• Ramos-Campo D, Martínez-Guardado I, Olcina G, Marín-Pagán C, Martínez-Noguera F, Carlos-Vivas J, et al. Effect of high-intensity resistance circuit-based training in hypoxia on aerobic performance and repeat sprint ability. Scandinavian journal of medicine & science in sports. 2018;28(10):2135-43.

  BACKGROUND

• Márquez G, Romero-Arenas S, Marín-Pagán C, Vera-Ibañez A, Fernandez Del Olmo M, Taube W. Peripheral and central fatigue after high intensity resistance circuit training. Muscle & nerve. 2017;56(1):152-9.

  BACKGROUND

MeSH Terms

Conditions

Behavior, Addictive

Condition Hierarchy (Ancestors)

Compulsive Behavior; Impulsive Behavior; Behavior

Study Officials

• Zobia Naseem, MS

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 21, 2025
• First Posted: April 22, 2026
• Study Start: September 30, 2025
• Primary Completion: January 30, 2026
• Study Completion: January 30, 2026
• Last Updated: April 22, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)