Development and Evaluation of an e-Mental Health Program for Depressive Symptoms

NCT07544758 | Completed

• 1 other identifier: NYMCTU
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled trial evaluates the effectiveness of an electronic mental health program (e-MHP) in reducing depressive symptoms among adults. The study also compares outcomes between clinical and nonclinical populations.

Conditions

Depressive Symptoms

Keywords

Depressive Symptoms; e-Mental Health; suicide prevention

Outcome Measures

Primary Outcomes (1)

• Change in Depression Severity

  Depression severity will be assessed using a standardized depression scale. Scores will be analyzed as continuous variables. Unit of Measure: Scale score (e.g., 0-27) Interpretation: \<5 = normal 5-9 = mild 10-14 = moderate 15-19 = moderately severe ≥20 = severe

  From enrollment to the end of intervention at 12 weeks. Post-test is held at 12 weeks after the intervention.

Other Outcomes (3)

• Change in Anhedonia

  From enrollment to the end of intervention at 12 weeks. Post-test is held at 12 weeks after the intervention.

• Change in Self-Esteem

  From enrollment to the end of intervention at 12 weeks. Post-test is held at 12 weeks after the intervention.

• Effectiveness analysis of a digital mental health program intervention on positive and negative suicide ideation.

  From enrollment to the end of intervention at 12 weeks. Post-test is held at 12 weeks after the intervention.

Study Arms (2)

Digital mental health program group

EXPERIMENTAL

A 12-week digital mental health program with nine interactive online modules addressing depression literacy, cognitive reframing, emotional acceptance, behavioral activation, interpersonal skills, relaxation, healthy lifestyle, and positive psychology. Modules (\~30 min each) were self-paced, with interactive exercises to reinforce skill use.

Behavioral: digital mental health program

control group

NO INTERVENTION

Participants did not receive the digital mental health program and continued their usual daily routines without additional intervention.

Interventions

digital mental health program BEHAVIORAL

The digital mental health program comprises nine interactive online modules that target knowledge of depression, cognitive reframing, emotional acceptance, behavioral activation, interpersonal skills, relaxation, a healthy lifestyle, and positive psychology.

Digital mental health program group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

Sponsors & Collaborators

• Chang Hsiu-Ju: lead
• National Science and Technology Council, Taiwan: collaborator

Study Sites (1)

National Yang Ming Chiao Tung University

Taipei, Taiwan, 155, Taiwan

Location

MeSH Terms

Conditions

Depression; Suicide Prevention

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Suicide; Self-Injurious Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 17, 2025
• First Posted: April 22, 2026
• Study Start: May 1, 2023
• Primary Completion: January 31, 2024
• Study Completion: January 31, 2024
• Last Updated: April 22, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)