Pediatric Renal Emergencies: Presentations and Outcomes at Sohag University Hospitals

NCT07543549 | Not Yet Recruiting

• 1 other identifier: Soh-med-25-7-20MS
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

Renal diseases in children present with a wide spectrum of clinical manifestations, ranging from mild urinary abnormalities to severe acute kidney injury requiring urgent management. Early recognition in the emergency setting is essential to improve outcomes, yet data on pediatric renal emergencies in Upper Egypt remain limited. This prospective cohort study aims to characterize the clinical presentations of renal diseases among children presenting to the emergency room at Sohag University Hospitals, determine the prevalence of specific renal conditions, and evaluate immediate management outcomes and short-term follow-up after discharge.

Conditions

Kidney Diseases

Outcome Measures

Primary Outcomes (1)

• Frequency of Clinical Presentations and Final Diagnoses of Pediatric Renal Diseases

  Percentage (%) of patients presenting with specific clinical features (e.g., edema, hematuria, oliguria, hypertension) assessed by clinical examination and initial laboratory investigations. Distribution (%) of final diagnoses (e.g., acute kidney injury, urinary tract infection, congenital anomalies, glomerular diseases) based on clinical evaluation, laboratory results, and imaging studies.

  At baseline (emergency room presentation) through hospital stay (up to discharge, typically within 7 days)

Study Arms (1)

Pediatric patients with renal diseases

Other: Standard emergency room management

Interventions

Standard emergency room management OTHER

Participants receive routine clinical assessment, investigations, and management according to Sohag University Hospitals emergency protocols. No study-specific intervention is applied.

Pediatric patients with renal diseases

Eligibility Criteria

• Age: 1 Month - 18 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population will include children aged 1 month to 18 years presenting to the emergency room of Sohag University Hospitals with clinical features suggestive of renal involvement. This includes both previously healthy children with new-onset symptoms and those with known renal diseases presenting with acute exacerbations. Patients will undergo routine clinical evaluation, laboratory investigations, and imaging as part of standard care, and will be followed during their hospital stay and after discharge.

You may qualify if:

• Children aged 1 month to 18 years. Presentation to the emergency room at Sohag University Hospitals with signs and/or symptoms suggestive of renal involvement (e.g., edema, hematuria, oliguria/anuria, flank pain, hypertension).
• Patients with a known history of renal disease presenting with acute exacerbation.
• Written informed consent obtained from parents or legal guardians.

You may not qualify if:

• Incomplete or missing essential clinical, laboratory, or imaging data. Refusal or inability to obtain written informed consent from parents or legal guardians.
• Patients with suspected renal symptoms later confirmed to have non-renal causes.
• Patients who received renal replacement therapy prior to presentation at another facility.

Sponsors & Collaborators

• Sohag University: lead

MeSH Terms

Conditions

Kidney Diseases

Condition Hierarchy (Ancestors)

Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Central Study Contacts

Fady Medhat

CONTACT

00201284408988; Fadymf96@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Pediatric resident

Study Record Dates

• First Submitted: March 29, 2026
• First Posted: April 22, 2026
• Study Start (Estimated): June 5, 2026
• Primary Completion (Estimated): July 5, 2027
• Study Completion (Estimated): October 5, 2027
• Last Updated: April 22, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share