NCT07540936

Brief Summary

Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life. Non-pharmacological interventions, such as exercise-based approaches, are increasingly used to support symptom management in these patients. This study aimed to evaluate the effects of an eight-week online yoga program on exercise capacity, dyspnea severity, respiratory function, and quality of life in adults with non-cystic fibrosis bronchiectasis. A total of 70 participants were randomly assigned to either a yoga intervention group or a control group. The yoga group participated in supervised online sessions three times per week, including breathing exercises, postures, and relaxation techniques, while the control group received usual care without additional intervention. Outcomes were assessed at baseline and after eight weeks using pulmonary function tests, the six-minute walk test (6MWT), the Modified Medical Research Council (mMRC) Dyspnea Scale, and the St. George's Respiratory Questionnaire (SGRQ). The study investigated whether yoga could provide a safe and effective complementary approach to improve symptoms and functional capacity in individuals with bronchiectasis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 15, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 20, 2025

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 15, 2025

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

April 8, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

April 21, 2026

Completed
Last Updated

April 21, 2026

Status Verified

April 1, 2026

Enrollment Period

5 months

First QC Date

April 8, 2026

Last Update Submit

April 17, 2026

Conditions

Keywords

YogaBronchiectasisPulmonary RehabilitationQuality of LifeRespiratory Function

Outcome Measures

Primary Outcomes (1)

  • 6-Minute Walk Distance (6MWT)

    The change in functional exercise capacity assessed by the six-minute walk test (6MWT), measured as the distance (in meters) walked in six minutes.

    Baseline and 8 weeks

Secondary Outcomes (7)

  • Dyspnea Severity (mMRC Scale)

    Baseline and 8 weeks

  • Health-Related Quality of Life (SGRQ)

    Baseline and 8 weeks

  • FEV1

    Baseline and 8 weeks

  • FVC

    Baseline and 8 weeks

  • FEV1/FVC

    Baseline and 8 weeks

  • +2 more secondary outcomes

Study Arms (2)

Yoga Group

EXPERIMENTAL

Participants in this group received an eight-week supervised online yoga program consisting of breathing exercises, postures (asanas), and relaxation techniques, performed three times per week (24 sessions in total).

Behavioral: Yoga Program

Control Group

NO INTERVENTION

Participants in this group received usual care without any additional intervention during the study period

Interventions

Yoga ProgramBEHAVIORAL

The intervention consisted of an eight-week online supervised yoga program including breathing exercises (pranayama), physical postures (asanas), and relaxation techniques. Sessions were conducted three times per week, totaling 24 sessions. The program was designed to improve respiratory control, chest expansion, and overall physical awareness.

Yoga Group

Eligibility Criteria

Age30 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Adults aged 30-55 years
  • Diagnosed with non-cystic fibrosis bronchiectasis based on clinical and radiological findings
  • Clinically stable condition
  • No participation in a structured exercise program within the previous 3 months
  • Voluntary agreement to participate

You may not qualify if:

  • Presence of additional respiratory diseases
  • Acute exacerbation or antibiotic use within the previous 4 weeks
  • Physical or cognitive impairments limiting participation
  • Age above 55 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istanbul Medipol University, Faculty of Physiotherapy and Rehabilitation

Istanbul, Beykoz, 34810, Turkey (Türkiye)

Location

MeSH Terms

Conditions

BronchiectasisRespiratory Aspiration

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesRespiration DisordersPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
Due to the nature of the intervention (yoga program), neither participants nor investigators were blinded to group allocation.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants were randomly assigned to either a yoga intervention group or a control group in a parallel design. The intervention group received an eight-week supervised online yoga program, while the control group received usual care without additional intervention.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

April 8, 2026

First Posted

April 21, 2026

Study Start

January 15, 2025

Primary Completion

June 20, 2025

Study Completion

October 15, 2025

Last Updated

April 21, 2026

Record last verified: 2026-04

Locations