NCT07540247

Brief Summary

This study aims to compare the effects of neuroathletic training, reactive training, and routine team training in American football players. American football requires not only strength, speed, agility, and balance, but also rapid reaction, decision-making, and appropriate motor responses. Therefore, training approaches targeting the nervous system and reaction skills may contribute to both performance enhancement and injury risk reduction. Active American football players aged 18-30 are randomly assigned to neuroathletic training, reactive training, or control groups. The intervention groups participate in additional exercise sessions twice a week for four weeks, while the control group continues routine team training only. Assessments are performed before and after the intervention period. Outcome measures include Y Balance Test, Functional Movement Screen, Reactive Balance Test, core endurance test, and sit-and-reach test. These assessments are used to examine reaction performance, dynamic balance, postural control, movement quality, core endurance, and flexibility. The findings are expected to help identify the most effective training approach for improving performance and reducing injury risk in American football players.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 12, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 8, 2026

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

April 11, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

April 20, 2026

Completed
Last Updated

April 20, 2026

Status Verified

April 1, 2026

Enrollment Period

3 months

First QC Date

April 11, 2026

Last Update Submit

April 17, 2026

Conditions

Outcome Measures

Primary Outcomes (3)

  • Functional Movement Screen

    The Functional Movement Screen (FMS) consists of seven movement tasks designed to assess the balance between mobility and stability: deep squat, hurdle step, inline lunge, shoulder mobility, active straight leg raise, trunk rotary stability, and trunk stability push-up. The test was administered using a standard test kit, and each movement was scored on a scale from 0 to 3 according to the standard scoring system. In the presence of pain, the relevant movement was recorded as 0 points (Altundağ et al., 2021).

    At baseline and immediately after the 4-week intervention

  • Y Balance Test

    Dynamic balance and postural control were assessed using the Y Balance Test. Participants stood on the fixed platform with their non-dominant lower extremity while reaching in the anterior, posteromedial, and posterolateral directions with the contralateral lower extremity. Three trials were performed in each direction, and reach distances were normalized to lower extremity length to calculate the composite score. Lower extremity length was measured as the distance between the anterior superior iliac spine and the medial malleolus (Unver et al., 2020).

    At baseline and immediately after the 4-week intervention

  • Reactive Balance Test

    The Reactive Balance Test was used to assess reactive postural control and visuomotor response performance associated with injury risk. This test consisted of the integration of the Y Balance Test setup with an LED-based light system (ReactionX) controlled via a smartphone application. The LED lights were positioned at 80% of the participants' maximum reach distance in each direction during the Y Balance Test. Participants were instructed to maintain balance in the standard starting position and deactivate the randomly illuminated LED lights as quickly as possible. A total of 45 visual stimuli were presented at varying intervals ranging from 0.5 to 2.5 seconds to minimize anticipatory effects. Test outcomes were recorded as visuomotor reaction time (ms) and accuracy (%). The test was performed twice; the first trial was considered a familiarization trial, and the results of the second trial were used for analysis (Tekin et al., 2025).

    At baseline and immediately after the 4-week intervention

Secondary Outcomes (2)

  • Core Endurance Test

    At baseline and immediately after the 4-week intervention

  • Sit-and-Reach Test

    At baseline and immediately after the 4-week intervention

Study Arms (3)

Neuroathletic Training Group

EXPERIMENTAL
Other: Neuroathletic Training

Reactive Training Group

EXPERIMENTAL
Other: Reactive Training

Control Group

NO INTERVENTION

Interventions

A structured exercise program designed to improve the integration of visual, vestibular, and proprioceptive inputs in order to enhance motor control, balance, reaction ability, coordination, and physical performance. Participants in this group receive neuroathletic exercises in addition to routine team training, twice weekly for 4 weeks, with each session lasting 10-15 minutes.

Neuroathletic Training Group

Participants receive a reactive training program in addition to routine team training. The program includes exercises performed with a light-based system and is designed to improve reaction speed, visual-motor response, dynamic balance, coordination, and decision-making ability. Training is performed twice weekly for 4 weeks, with sessions lasting 10-15 minutes.

Reactive Training Group

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Aged 18-30 years Holding an active American football license during the study season Competing at the university, semi-professional, or professional level Regular participation in team training (6-10 hours per week) At least one year of continuous competitive American football experience Having a structured training background in American football Free from color blindness Free from attention-related disorders Free from any health condition that could affect neuromuscular, reactive, or sport-specific performance

You may not qualify if:

  • Injury within the previous 3 months resulting in absence from training or competition for more than 2 weeks Upper or lower extremity surgery within the previous 6 months History of neurological, vestibular, or cardiovascular disorders that could interfere with neuroathletic training or performance assessments COVID-19 infection within the previous 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pamukkale University

Denizli, Kınıklı, 20160, Turkey (Türkiye)

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcome assessment and statistical analysis were performed by individuals blinded to group allocation.
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Lecturer

Study Record Dates

First Submitted

April 11, 2026

First Posted

April 20, 2026

Study Start

December 12, 2025

Primary Completion

March 1, 2026

Study Completion

April 8, 2026

Last Updated

April 20, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations