Innovative Approaches to Hypertension Management in High-Risk Emergency Department Populations

NCT07539597 | Recruiting

• 2 other identifiers: STUDY-25-003631P50MD019475
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

This single-center, single-arm quasi-experimental study will assess the feasibility and acceptability of a community health worker (CHW)-led intervention to address social determinants of health (SDOH) among emergency department patients with hypertension. At enrollment, participants (N=15) will complete standardized SDOH surveys in REDCap, and CHWs will facilitate referrals to local community-based organizations that address identified social needs. With participant consent, the study will also include medical record review through EPIC and Healthix to evaluate healthcare utilization-including emergency department visits, hospitalizations, and outpatient encounters-during the one-year period before and after the index ED visit.

Conditions

Asymptomatic Hypertension

Keywords

Hypertension; Social Determinates of Health; Community Health Worker

Outcome Measures

Primary Outcomes (2)

• Number of participants on study at 3 months

  Number of participants on study at 3 months to assess retention

  3 months

• Number of intervention engagement

  Number of interventions engagement based on number of types of CHW encounters

  6 months

Secondary Outcomes (2)

• Acceptability of Intervention Measure (AIM)

  baseline, 3 months, 6 months

• Intervention Appropriateness Measure (IAM)

  baseline, 3 months, 6 months

Study Arms (1)

Participants with Hypertension

EXPERIMENTAL

Participants with hypertension in high-risk Emergency Department populations

Behavioral: Community Health Worker engagement

Interventions

Community Health Worker engagement BEHAVIORAL

Engagement with Community Health Worker who will facilitate referrals to local community-based organizations

Participants with Hypertension

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years and older who reside in the 5 boroughs of NYC,
• whom speak English or Spanish,
• have a known diagnosis of hypertension, and
• have uncontrolled hypertension, defined as two measures of systolic blood pressure (SBP) ≥140 mmHg or diastolic blood pressure (DBP) ≥ 90 mmHg obtained during their ED visit.

You may not qualify if:

• Patients who are unable to consent,
• pregnant patients,
• patients with a history of end stage renal disease, a history of heart failure or a BMI of greater than 50.

Sponsors & Collaborators

• Icahn School of Medicine at Mount Sinai: lead
• National Institute on Minority Health and Health Disparities (NIMHD): collaborator

Study Sites (1)

Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States

RECRUITING

Related Publications (4)

• Ahuja R, Ayala C, Tong X, Wall KH, Fang J. Public Awareness of Health-Related Risks From Uncontrolled Hypertension. Preventing Chronic Disease. 2018;15.

  BACKGROUND

• Akinyelure PO, Jaeger CB, Oparil S, et al. Social Determinants of Health and Uncontrolled Blood Pressure in a National Cohort of Black and White US Adults: the REGARDS Study. Hypertension. 2023;80(7):1403-1413.

  BACKGROUND

• Ware SK, Chidume T, Chou C. Social determinants of health and preventable emergency department patient encounters among adults with hypertension. Public Health Nursing. 2023;40(1):171-174.

  BACKGROUND

• Foster B, Dawood K, Pearson C, Manteuffel J, Levy P. Community Health Workers in the Emergency Department-Can they Help with Chronic Hypertension Care. Current Hypertension Reports. 2019;21(7).

  BACKGROUND

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Officials

• Marcee Wilder, MD MPH

  ISMMS

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Cindy Clesca

CONTACT

212-824-8057; cindy.clesca@mountsinai.org

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 13, 2026
• First Posted: April 20, 2026
• Study Start: February 12, 2026
• Primary Completion (Estimated): July 31, 2026
• Study Completion (Estimated): July 31, 2026
• Last Updated: April 20, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)