Implementing Transcranial Direct Current Stimulation in a Rehabilitation Setting

NCT07535788 | Not Yet Recruiting FDA Device

• 1 other identifier: IRB#23721124
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study looks at whether transcranial Direct Current Stimulation (tDCS) can be effectively implemented in inpatient and outpatient rehabilitation settings during routine speech therapy for people who recently had a stroke and now have aphasia (difficulty speaking or understanding language)

Conditions

Aphasia; Stroke

Outcome Measures

Primary Outcomes (2)

• Nasa Taskload Index (NTI)

  The NASA Task Load Index (NTI) is a widely used tool for measuring how demanding a task feels to a person. It captures subjective workload, meaning it asks individuals to rate how challenging a task was for them. It was developed by NASA researchers in the 1980s to better understand how mental and physical demands affect performance

  3 months, 6 months and 1 year (after the start of data collection, approximately)

• Theoretical Domain Framework (TDF) questionnaire

  The Theoretical Domains Framework (TDF) is a structured approach used to understand why people do or do not change behavior in healthcare and other settings. It brings together key concepts from multiple behavior-change theories into a single framework to help identify barriers and facilitators to implementing new practices.

  at baseline, as well as 3 months, 6 months and 1 year (after the start of data collection, approximately)

Secondary Outcomes (1)

• Western Aphasia Battery Revised (WABr)

  at patient's admission and discharge (around 3 weeks after admission)

Other Outcomes (1)

• Adverse Event Questionnaire (AEQ)

  3 months and 6 months (after the start of data collection, approximately)

Interventions

transcranial direct current stimulation (tDCS) DEVICE

20 minute anodal tDCS (1mA) to the left inferior frontal (Broca) area, concurrent with speech and language therapy by a trained speech language pathologist (SLP) over their stay (during at least 5 sessions)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

adult stroke patients with aphasia of inpatient and outpatient settings of Casa Colina Hospital and Centers for Healthcare

You may qualify if:

• ischemic or hemorrhagic stroke
• aphasia

You may not qualify if:

• not a patient at either inpatient and outpatient settings of Casa Colina Hospital and Centers for Healthcare

Sponsors & Collaborators

• Casa Colina Hospital and Centers for Healthcare: lead

Related Publications (4)

• Williams EER, Sghirripa S, Rogasch NC, Hordacre B, Attrill S. Non-invasive brain stimulation in the treatment of post-stroke aphasia: a scoping review. Disabil Rehabil. 2024 Aug;46(17):3802-3826. doi: 10.1080/09638288.2023.2259299. Epub 2023 Oct 13.

  PMID: 37828899 BACKGROUND

• Picano C, Quadrini A, Pisano F, Marangolo P. Adjunctive Approaches to Aphasia Rehabilitation: A Review on Efficacy and Safety. Brain Sci. 2021 Jan 2;11(1):41. doi: 10.3390/brainsci11010041.

  PMID: 33401678 BACKGROUND

• Breining BL, Sebastian R. Neuromodulation in post-stroke aphasia treatment. Curr Phys Med Rehabil Rep. 2020 Jun;8(2):44-56. doi: 10.1007/s40141-020-00257-5. Epub 2020 Feb 22.

  PMID: 33344066 BACKGROUND

• Khan A, Yuan K, Bao SC, Ti CHE, Tariq A, Anjum N, Tong RK. Can Transcranial Electrical Stimulation Facilitate Post-stroke Cognitive Rehabilitation? A Systematic Review and Meta-Analysis. Front Rehabil Sci. 2022 Feb 10;3:795737. doi: 10.3389/fresc.2022.795737. eCollection 2022.

  PMID: 36188889 BACKGROUND

MeSH Terms

Conditions

Aphasia; Stroke

Interventions

Transcranial Direct Current Stimulation

Condition Hierarchy (Ancestors)

Speech Disorders; Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Electric Stimulation Therapy; Therapeutics; Convulsive Therapy; Psychiatric Somatic Therapies; Behavioral Disciplines and Activities; Electroshock; Psychological Techniques

Central Study Contacts

Caroline Schnakers, PhD

CONTACT

3108061443; cschnakers@casacolina.org

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Director of Research

Study Record Dates

• First Submitted: April 1, 2026
• First Posted: April 17, 2026
• Study Start: May 4, 2026
• Primary Completion (Estimated): May 4, 2027
• Study Completion (Estimated): May 30, 2027
• Last Updated: April 17, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share