The Effect of Myopia-Control Contact Lenses in New Zealand Chinese Children

NCT07535749 | Recruiting Phase 3

• 1 other identifier: Myopia-Control Contact Lenses
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

The study will employ a randomized, controlled, investigator-masked paired-eye comparison design to evaluate the effects of two myopia-control contact lenses-MiSight 1 Day and Abiliti 1-Day-in New Zealand Chinese children. The study duration will be 6 months, with assessments conducted at baseline, 2 weeks, 3 months, and 6 months. The clinical research will be conducted at the Auckland Myopia Clinic (New Zealand) and will follow a standard clinical routine for children with early myopia, the only difference being the randomizing of the MiSight and Abiliti contact lenses between the two eyes of the participants.

Conditions

Myopia Progression

Keywords

myopia control; contact lenses

Outcome Measures

Primary Outcomes (2)

• Mean Spherical Equivalent Cycloplegic Refraction

  The dioptric refractive error as determined by retinoscopy following cycloplegic refraction

  Baseline, 2 weeks, 3 months, 6 months

• Axial length

  Ocular biometry measured with Myah biometer

  Baseline, 2 weeks, 3 months, 6 months

Secondary Outcomes (5)

• Children Dry Eye Questionnaire (CDEQ) response

  Baseline, 2 weeks, 3 months, 6 months

• Non-invasive Tear break-up time

  Baseline, 2 weeks, 3 months, 6 months

• Ocular Protection Index

  Baseline, 2 weeks, 3 months, 6 months

• Corneal punctate spots

  Baseline, 2 weeks, 3 months, 6 months

• Conjunctival punctate spots

  Baseline, 2 weeks, 3 months, 6 months

Study Arms (2)

MiSight Contact Lens

ACTIVE COMPARATOR

Commercially available myopia control contact lens

Device: MiSight Contact Lenses (CooperVision)

Abiliti 1-Day

ACTIVE COMPARATOR

Commercially available myopia control contact lens

Device: Albiliti 1-Day (Johnson and Johnson, VisionCare)

Interventions

MiSight Contact Lenses (CooperVision) DEVICE

Myopia Control Contact Lens

MiSight Contact Lens

Albiliti 1-Day (Johnson and Johnson, VisionCare) DEVICE

Myopia Control Contact Lens

Abiliti 1-Day

Eligibility Criteria

• Age: 7 Years - 11 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Spherical refractive error between -1.00D and -4.50D
• Astigmatism of ≤1.00D
• No history of orthokeratology or atropine use
• No ocular diseases or surgical history

You may not qualify if:

• o No ocular diseases or surgical history

Sponsors & Collaborators

• Aston University: lead

Study Sites (1)

Auckland Myopia Clinic

Auckland, 1052, New Zealand

RECRUITING

Central Study Contacts

James S Wolffsohn, BSc PhD DSc

CONTACT

+447833049245; j.s.w.wolffsohn@aston.ac.uk

Vivienne Wang, BSc

CONTACT

210269613@aston.ac.uk

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Contralateral eye study, randomised

Study Record Dates

• First Submitted: March 24, 2026
• First Posted: April 17, 2026
• Study Start: March 21, 2026
• Primary Completion (Estimated): November 30, 2026
• Study Completion (Estimated): December 30, 2026
• Last Updated: April 17, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

NZ (1)