NCT07534410

Brief Summary

Parameters related to cardiopulmonary exercise testing (CPET) are important objective indicators for evaluating cardiopulmonary function in patients with coronary heart disease. However, the clinical application of CPET parameters in the prognostic assessment of patients with coronary heart disease remains unclear. This is a retrospective cohort study designed to systematically collect real-world clinical data and long-term follow-up outcomes of patients with coronary heart disease. Through standardized follow-up, this study will investigate the association between CPET parameters and adverse clinical outcomes in patients with coronary heart disease, as well as the relevant risk factors.

Trial Health

65
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15,000

participants targeted

Target at P75+ for all trials

Timeline
15mo left

Started Apr 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress2%
Apr 2026Jun 2027

Study Start

First participant enrolled

April 7, 2026

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

April 9, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 16, 2026

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2027

Expected
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2027

Last Updated

April 16, 2026

Status Verified

December 1, 2025

Enrollment Period

10 months

First QC Date

April 9, 2026

Last Update Submit

April 9, 2026

Conditions

Coronary Heart Disease (CHD)

Outcome Measures

Primary Outcomes (1)

  • Cumulative incidence of Major Adverse Cardiovascular Events (MACE)

    The proportion of patients who experience an adjudicated Major Adverse Cardiovascular Event (MACE), defined as a composite endpoint consisting of non-fatal myocardial infarction, non-fata

    1 year

Secondary Outcomes (1)

  • All-cause mortality

    1 year

Study Arms (1)

Coronary Heart Disease Cohort

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients diagnosed with coronary heart disease in our hospital and who have completed cardiopulmonary exercise testing.

You may qualify if:

  • Our hospital has diagnosed coronary heart disease and conducted cardiopulmonary exercise tests.
  • Patients with complete clinical data.

You may not qualify if:

  • Uncontrolled heart failure (NYHA classification Ⅲ-IV grade).
  • Complications, such as moderate to severe anemia, tumors and lung diseases.
  • Complicated with valvular heart disease.
  • Unable to reach the anaerobic threshold during exercise.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Coronary Disease

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Xiang Xie, PhD

    First Affiliated Hospital of Xinjiang Medical University

    STUDY CHAIR

Central Study Contacts

Xiang Xie, PhD

CONTACT

+86-991-4366892xiangxie999@sina.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 9, 2026

First Posted

April 16, 2026

Study Start

April 7, 2026

Primary Completion (Estimated)

January 31, 2027

Study Completion (Estimated)

June 30, 2027

Last Updated

April 16, 2026

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share