Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital

NCT07526636 | Not Yet Recruiting

• 1 other identifier: AUCH-NGIT-2026
• Study Type: observational
• Target: 120
• Locations: 0 countries
• Sites: N/A

Brief Summary

This prospective observational study aims to evaluate the pattern, clinical presentation, complications, and short-term outcomes of neonates admitted with gastrointestinal emergencies to the NICU at Assiut University Children Hospital. Data will be collected from admission through discharge, including demographic, antenatal, natal, clinical, nutritional, laboratory, and radiological information, to identify the most common emergencies and factors associated with adverse outcomes.

Conditions

Necrotizing Enterocolitis; Intestinal Atresia; Malrotation; Hirschsprung Disease

Keywords

Neonate; NICU; Gastrointestinal emergency; Intestinal obstruction

Outcome Measures

Primary Outcomes (1)

• Prevalence of the most common gastrointestinal emergencies among neonates admitted to the NICU

  The prevalence of each type of neonatal gastrointestinal emergency will be calculated as the proportion of cases among all enrolled neonates admitted to the NICU during the study period. Diagnoses will be based on clinical, laboratory, and radiological findings.

  Up to 28 days (hospital stay)

Secondary Outcomes (3)

• Mortality Rate

  Up to 28 days (hospital stay

• Length of Hospital Stay

  From admission to discharge, up to 28 days

• Requirement for surgical intervention

  During hospitalization, up to 28 days

Eligibility Criteria

• Age: 1 Minute - 28 Days
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Neonates admitted to the NICU at Assiut University Children Hospital with gastrointestinal emergencies, including both term and preterm infants from 28 weeks gestational age, observed from admission through discharge.

You may qualify if:

• Neonates aged 0-28 days (corrected age if preterm)
• Admitted to the NICU with a clinical diagnosis of a gastrointestinal emergency requiring urgent intervention
• Written informed consent obtained from parent(s) or legal guardian(s)

You may not qualify if:

• Other gastrointestinal problems not requiring urgent intervention

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Enterocolitis, Necrotizing; Intestinal Atresia; Volvulus Of Midgut; Hirschsprung Disease; Intestinal Obstruction

Condition Hierarchy (Ancestors)

Enterocolitis; Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Intestinal Diseases; Digestive System Abnormalities; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Megacolon; Colonic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Of Pediatrics

Study Record Dates

• First Submitted: April 3, 2026
• First Posted: April 13, 2026
• Study Start (Estimated): May 1, 2026
• Primary Completion (Estimated): April 1, 2027
• Study Completion (Estimated): April 1, 2027
• Last Updated: April 13, 2026

Record last verified: 2026-04