NCT07525336

Brief Summary

This study aims to determine the effect of dry eye disease on intraocular lens power calculation and the postoperative refractive outcome.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
37mo left

Started Apr 2026

Typical duration for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 7, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 13, 2026

Completed
17 days until next milestone

Study Start

First participant enrolled

April 30, 2026

Expected
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2028

1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2029

Last Updated

April 13, 2026

Status Verified

April 1, 2026

Enrollment Period

2 years

First QC Date

April 7, 2026

Last Update Submit

April 7, 2026

Conditions

Dry Eye Disease (DED)Cataract (Post-operative Cataract Surgery Follow-up)

Keywords

dry eye diseasebiometryrefractive surprisephacoemulsification

Outcome Measures

Primary Outcomes (2)

  • Compare mean absolute error (MAE) between patients with and without DED

    2 yeras

  • Compare mean absolute error (MAE) between patients with and without DED

    2 years

Study Arms (2)

dry eye disease

dry eye disease patients who are not optimized before phacoemulsification

non dry eye disease

non dry eye disease patients before phacoemulsification

Procedure: dry eye disease optimization

Interventions

dry eye disease optimizationPROCEDURE

dry eye disease management prior to obtaining intraocular lens power calculation

non dry eye disease

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population will consist of adult patients aged 40 years and older diagnosed with cataract and scheduled for phacoemulsification surgery at Assiut University Hospital.

You may qualify if:

  • Age equals to or above 40 years old
  • cataract patient
  • suitable for phacoemulsification
  • clear corneal media

You may not qualify if:

  • previous corneal surgery
  • advanced glaucoma
  • corneal pathology (keratoconus, scarring)
  • retinal disease affecting vision
  • irregular astigmatism
  • contact lens use within the last 2 weeks

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Dry Eye SyndromesCataract

Condition Hierarchy (Ancestors)

Lacrimal Apparatus DiseasesEye DiseasesLens Diseases

Central Study Contacts

Ziad M.A Sayed

CONTACT

+201152373413mkkh30@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MBBCH

Study Record Dates

First Submitted

April 7, 2026

First Posted

April 13, 2026

Study Start (Estimated)

April 30, 2026

Primary Completion (Estimated)

April 30, 2028

Study Completion (Estimated)

April 30, 2029

Last Updated

April 13, 2026

Record last verified: 2026-04