Vesico-uterin Thickness and Sliding Sign in Term Pregnancies

NCT07523698 | Completed DMC

• 1 other identifier: 3015/12.2023
• Study Type: interventional
• Target: 117
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, our aim was to evaluate the relationship of the bladder to the uterus including vesicouterin thickness and sliding sign in term pregnancies with at least one previous cesarean section and compare to controls.

Conditions

Sliding Sign; Vesicouterin Thickness; Term Pregnancy; Adhesion; Bladder; Adhesions Uterus

Keywords

Vesicouterin thickness; sliding sign; intra-abdominal adhesions; repeat Cesarean section

Outcome Measures

Primary Outcomes (2)

• sliding sign

  The probe was placed just above the transverse skin scar and the patient was asked to take a deep breath or cough in order for the uterus to be observed sliding caudally under the parietal peritoneum and fascia transversalis. Presence of the sliding sign was described "positive" when sliding of the uterus against the abdominal wall was observed. When no movement of the uterus under the fascia, the sliding sign was considered "negative".

  The study will end when a sufficient number of patients is reached.

• Vesicouterin thickness

  The tissue between the uterus and bladder (vesicouterin thickness) was examined and mesasured.

  Approximately 6 months. The study will complete when required number of patients reached.

Study Arms (2)

intervention (study) group

ACTIVE COMPARATOR

repeated cesarean group

Other: ultrasound evaluation

control group

ACTIVE COMPARATOR

primigravid patients

Other: ultrasound evaluation

Interventions

ultrasound evaluation OTHER

The probe was placed just above the transverse skin scar and the patient was asked to take a deep breath or cough in order for the uterus to be observed sliding caudally under the parietal peritoneum and fascia transversalis. Presence of the sliding sign was described "positive" when sliding of the uterus against the abdominal wall was observed. When no movement of the uterus under the fascia, the sliding sign was considered "negative".

Also known as: Sliding sign, vesico-uterin thickness

control group; intervention (study) group

Eligibility Criteria

• Age: 18 Years - 45 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• years
• viable singleton third-trimester (37 weeks of gestation or later) pregnancies
• history of at least one previous cesarean section

You may not qualify if:

• uterine anomalies,
• intra-abdominal cysts or myomas,
• multiple pregnancies,
• history of additional intra-abdominal surgery,
• history of steroid use, collagen disorders,
• placental adhesion or invasion anomalies.

Sponsors & Collaborators

• Adana City Training and Research Hospital: lead

Study Sites (1)

University of Heath and Science Adana City Hospital

Adana, Yuregir, 01230, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Tissue Adhesions

Condition Hierarchy (Ancestors)

Cicatrix; Fibrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Gülsüm Uysal

  Department of Obstetrics and Gynecology, University of Health and Science Adana City Training and Research Hospital, Adana, Turkey

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ass. Professor Gulsum Uysal

Model Details: Pregnant women aged 18-45 years with singleton, viable third-trimester (37 weeks of gestation or later) pregnancies with the history of at least one previous cesarean section were included in the study. The control group consisted of healthy pregnant women in the third trimester with similar demographic characteristics who underwent elective (planned) cesarean delivery and had no obstetric or medical comorbidities. The aim was to evaluate the relationship of the bladder to the uterus including vesicouterin thickness and sliding sign in term pregnancies with at least one previous cesarean section and compare to controls. The relationship of the bladder to the uterus, whether it was below or above the symphysis pubis, slidign sign and vesicouterin thickness were noted.

Study Record Dates

• First Submitted: April 6, 2026
• First Posted: April 13, 2026
• Study Start: January 1, 2024
• Primary Completion: June 30, 2024
• Study Completion: June 30, 2024
• Last Updated: April 21, 2026

Record last verified: 2023-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)