Investigation on Suicide Risk Factors of Patients With Mood Disorders

NCT07523490 | Recruiting DMC

• 1 other identifier: MD-SU
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the level and distribution of suicide risk and learned suicide ability of patients with mood disorders, investigates the related risk factors of suicide and suicide ability formation of patients with mood disorders from multiple dimensions (biological, psychological, social and clinical perspectives) and clarifies their importance, forms a list of suicide risk factors, and establishes a prediction model of learned suicide ability formation. Upon enrollment, participants will undergo comprehensive assessments including blood and urine sample collection and scale evaluation. The collection of scientific blood and urine is mainly used for the exploration of molecular mechanism of disease occurrence and development, the discovery and verification of biomarkers. Scale evaluation includes: Beck Scale for Suicide Ideation , Columbia Suicide Severity Rating Scale,, Hamilton Depression Rating Scale , Hamilton Anxiety Rating Scale, PHQ-9, GAD-7, Personal and Social Function Scale , Schihan Disability Scale , Emotional Adjustment Difficulty Scale , Acquired Capability for Suicide Scale, Interpersonal Needs Questionnaire , Ottawa Self-Injury Scale, Chinese version of Stress Perception Scale and Beck Hopelessness Scale . Follow-up was carried out for 3 months, including whether suicide/self-injury occurred, current status, and some baseline questionnaires (such as BSI-CV, GAD-7, PHQ-9, HAMD-17,HAMA, etc.).

Conditions

Suicide; Mood Disorders

Keywords

Mood Disorders; suicide; Biological Mechanism; prediction model

Outcome Measures

Primary Outcomes (1)

• Columbia Suicide Severity Rating Scale

  Columbia Suicide Severity Rating Scale (C-SSRS) is a tool for evaluating the risk of individual suicide. It includes a series of questions to evaluate the frequency, intensity, persistence and concreteness of individual suicide behavior in the past period of time. The purpose of C-SSRS scale is to distinguish between suicidal ideation and suicidal attempt and higher scores mean a worse outcome. Developed by researchers from Columbia University, the scale is widely used in clinical and research fields to help identify and manage suicide risks.

  baseline, 3 months

Secondary Outcomes (8)

• Beck Scale for Suicide Ideation

  baseline, 3 months

• Hamilton Depression Rating Scale

  baseline, 3 months

• Hamilton Anxiety Rating Scale

  baseline, 3 months

• Patient Health Questionnare

  baseline, 3 months

• Generalized Anxiety Disorder

  baseline, 3 months

Study Arms (1)

patients with mood disorders

1. Age: 16 to 60 years old; 2. seeing a doctor in a psychiatric clinic or a general hospital; 3. Willing to cooperate in this research project; 4. Sign the informed consent form (minors also need to obtain the informed consent signature of the guardian); 5. Meet the diagnostic criteria of ICD-11 mood disorder.

Eligibility Criteria

• Age: 16 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

This study will recruit 300 patients meeting the diagnostic criteria of ICD-11 mood disorder.The 300 subjects, aged16 to 60 years old, come from Tianjin Anding Hospital's inpatient/outpatient services and must consent to participate. Exclusion Criteria are as follows:(1) unable to understand the contents of the questionnaire;(2) Serious organic diseases such as cardiovascular disease, brain disease, liver disease and kidney disease, and weak body, which affect the respondents of the questionnaire;(3) Other circumstances that make it impossible or unwilling to cooperate with the completion of the questionnaire.

You may qualify if:

• Age: 16 to 60 years old;
• seeing a doctor in a psychiatric clinic or a general hospital;
• Willing to cooperate in this research project;
• Sign the informed consent form (minors also need to obtain the informed consent signature of the guardian);
• Meet the diagnostic criteria of ICD-11 mood disorder.

You may not qualify if:

• unable to understand the contents of the questionnaire;
• Serious organic diseases such as cardiovascular disease, brain disease, liver disease and kidney disease, and weak body, which affect the respondents of the questionnaire;
• Other circumstances that make it impossible or unwilling to cooperate with the completion of the questionnaire.

Sponsors & Collaborators

• Tianjin Anding Hospital: lead

Study Sites (1)

Tianjin Anding Hospital

Tianjin, Tianjin Municipality, 300000, China

RECRUITING

MeSH Terms

Conditions

Mood Disorders; Suicide

Condition Hierarchy (Ancestors)

Mental Disorders; Self-Injurious Behavior; Behavioral Symptoms; Behavior

Central Study Contacts

Xue Tian

CONTACT

+86-13602182093; 576491743@qq.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 5, 2026
• First Posted: April 13, 2026
• Study Start: December 31, 2025
• Primary Completion (Estimated): September 30, 2027
• Study Completion (Estimated): September 30, 2027
• Last Updated: April 22, 2026

Record last verified: 2026-04

Locations

CN (1)