Psychiatric Disorders in Dermatiological Diseases

NCT07521813 | Not Yet Recruiting

• 1 other identifier: Soh-Med-26-3-14MS
• Study Type: observational
• Target: 500
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study:

1. 1.Evaluate the presence of body dysmorphic disorder in children with dermatological diseases compared to healthy controls.
2. 2.Assess the effect of these skin diseases on the quality of life in those children.

Conditions

Body Dysmorhpic Disorder

Outcome Measures

Primary Outcomes (2)

• Evaluation of Body Dysmorphic Disorder in Children with Dermatological Diseases

  Evaluate the presence of body dysmorphic disorder in children with dermatological diseases compared to healthy controls. The study will include 250 children of both sexes aged from six to less than 18 years presented with various chronic skin diseases, diagnosed clinically , by dermoscopy and by biopsy if needed, and 250 age and sex matched healthy controls . Assessment of the severity of the dermatological diseases according to available valid severity scores will be done . Body Dysmorphic Disorder Questionnaire Dermatology Version will be done to identify symptoms of body dysmorphic disorder with valid standardized arabic version . The body dysmorphic disorder questionnaire is a brief, validated questionnaire used to identify patients having symptoms of BDD. It uses close-ended questions and identifies if participants' concerns regarding appearance are a source of preoccupation and identifies the grade of distress or interference with social and occupational functioning .

  From Apri 2026 to April 2027

• Assess the effect of skin diseases on the quality of life of children

  Assess the effect of skin diseases on the quality of life in children by using Children's Dermatology Life Quality Index questionnaire (CDLQI) that used to evaluate the psychosocial impact of skin disease with valid standardized Arabic version . The study will include 250 children of both sexes aged from six up to less than 18 years presenting with various chronic skin diseases, diagnosed clinically, by dermoscopy and by biopsy if needed, and 250 age and sex matched healthy controls then Children's Dermatology Life Quality Index questionnaire (CDLQI) will be assessed with a valid standardized Arabic version . The Children's Dermatology Life Quality Index (CDLQI) is a validated questionnaire to assess the impact of skin diseases on the quality of life of children. It evaluates the effect of dermatological conditions on physical symptoms, emotional well-being, daily activities, social interactions, school performance, and treatment.

  From April 2026 to April 2027

Interventions

Questionnaire and Physical Exam OTHER

The Body Dysmorphic Disorder Questionnaire (BDDQ) : The BDD-Q is a brief, validated self-administered questionnaire that is used to identify patients having symptoms of BDD. It uses close-ended questions and identifies if participants' concerns regarding appearance are a source of preoccupation. It also identifies the grade of distress or interference with social and occupational functioning caused by these concerns . It has good validity, high sensitivity (100%) and specificity (89- 93%) for screening for BDD . BDD diagnosis is likely if answers to question (1) (preoccupation) are yes to both parts, answers to question 3 (significant stress) include yes to any of the questions and answers to question (4) (time spent thinking about defect) include b or c choices.

Eligibility Criteria

• Age: 6 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study will include 250 patients with dermatological diseases and 250 age and sex matched healthy controls. From Dermatology outpatient clinics, Sohag University Hospitals, Faculty of Medicine Sohag University.

You may qualify if:

• The study will include 250 children of both sexes aged from six up to less than 18 years presenting with various chronic skin diseases, diagnosed clinically, by dermoscopy and by biopsy if needed, and age and sex matched healthy controls.
• Ability of the child and caregiver to understand and respond to the questionnaires.

You may not qualify if:

• Children with diagnosed psychiatric disorders other than BDD (e.g., severe depression, autism spectrum disorder).
• Children with chronic systemic illness affecting body image or any other debilitating acute , chronic illness or surgical problems e.g.: short stature, hypothyroidism, osteochondral defects and obesity.

Sponsors & Collaborators

• Sohag University: lead

Related Publications (4)

• Arumugham SS, Narayanaswamy JC, Balachander S, Sharma E, Jaisoorya TS, Reddy SC, Siddiqui AM, Desouza A, Shah PS, Reddy YJ. Clinical practice guidelines for obsessive-compulsive disorder: 2025 update. Indian J Psychiatry. 2026 Jan;68(1):44-67. doi: 10.4103/indianjpsychiatry_1259_25. Epub 2026 Jan 27.

  PMID: 41694048 BACKGROUND

• Ruck C, Mataix-Cols D, Feusner JD, Shavitt RG, Veale D, Krebs G, Fernandez de la Cruz L. Body dysmorphic disorder. Nat Rev Dis Primers. 2024 Dec 5;10(1):92. doi: 10.1038/s41572-024-00577-z.

  PMID: 39639018 BACKGROUND

• Sa B, Khalil N, Edwards E, Smith A, Franca K. Pediatric Psychodermatology: Advancing Therapy through Integrated Care. Dermatol Ther (Heidelb). 2026 Mar;16(3):1455-1472. doi: 10.1007/s13555-026-01673-6. Epub 2026 Feb 16.

  PMID: 41697633 BACKGROUND

• Salari N, Heidarian P, Hosseinian-Far A, Babajani F, Mohammadi M. Global Prevalence of Anxiety, Depression, and Stress Among Patients with Skin Diseases: A Systematic Review and Meta-analysis. J Prev (2022). 2024 Aug;45(4):611-649. doi: 10.1007/s10935-024-00784-0. Epub 2024 Jun 1.

  PMID: 38822990 BACKGROUND

MeSH Terms

Interventions

Surveys and Questionnaires; Restraint, Physical

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health; Behavior Control; Therapeutics; Immobilization

Study Officials

• Soha Hishmat Aboeldahab, Professor

  Sohag University

  STUDY DIRECTOR

Central Study Contacts

Aya Abdelhaseb Abdellatif, Resident doctor

CONTACT

00201142639444; aya.abdelhasseb@med.sohag.edu.eg

Zeinab Abuelbaha Gouda, Lecturer

CONTACT

00201025863400; Zeinabgouda3415@med.sohag.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of dermatology

Study Record Dates

• First Submitted: March 31, 2026
• First Posted: April 13, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): April 1, 2027
• Last Updated: April 13, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share