ABXvsCHX
Enamel-repair Microcrystal Mouthwash Enriched With an Antibacterial Complex (ABX) Versus Chlorhexidine (CHX) Mouthwash as an Adjunct to Non-surgical Periodontal Therapy
Sponsor study identifier
interventional
40
1 country
1
Study Start
September 9, 2025
Actual (reported)Primary Completion
November 1, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
March 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
The study aims to compare the efficacy of a novel mouthwash based on microRepair ABX and an antibacterial complex with that of 0.12% chlorhexidine, both used as adjuncts to scaling and root planing.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 9, 2025
Actual (reported)April 2, 2026
Actual (reported)April 9, 2026
Actual (reported)November 1, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
March 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Probing depth
Probing Depth (PD), measured in millimeters (mm) using a PCP 15 UNC periodontal probe. PD represents the distance from the gingival margin to the base of the periodontal pocket. The measurement range is from 0 to 15 mm. Higher values indicate deeper periodontal pockets and a worse periodontal condition.
From enrollment to the end of treatment at 12 weeks and at 24 weeks
full mouth bleeding score
Full Mouth Bleeding Score (FMBS), expressed as the percentage (%) of sites exhibiting bleeding on probing out of the total number of sites examined. The scale ranges from 0% to 100%, where higher percentages indicate more gingival inflammation and a worse outcome.
from baseline to 12 and 24 weeks after full mouth disinfection
clinical attachment level - CAL
From baseline to 12 and 24 weeks after full mouth disinfection
Full mouth plaque score
from baseline to 12 and 24 weeks after full mouth disinfection
dentin hypersensitivity
baseline, 12 weeks and 24 weeks
Patient satisfaction
2 weeks after the non surgical periodontal treatment
NSPT + ABX
NSPT + CHX 0,12%
Group A: a novel mouthwash with microRepair ABX will be used for the first timen in adjunct to non surgical periodontal therapy
Group B - chlorhexidine mouthwash in adjunct to nonsurgical periodontal therapy
Fabrizio Guerra
Roma, rm, 00161, Italy
Cobb CM. Clinical significance of non-surgical periodontal therapy: an evidence-based perspective of scaling and root planing. J Clin Periodontol. 2002 May;29 Suppl 2:6-16.
First Submitted
April 2, 2026
First Posted
April 9, 2026
Study Start
September 9, 2025
Actual (reported)Primary Completion
November 1, 2026
EstimatedRegistry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
March 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
April 21, 2026
Record last verified: 2026-03
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Source: ClinicalTrials.gov.
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