Conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique With or Without Hayman Sutures
1 other identifier
interventional
48
0 countries
N/A
Brief Summary
This study evaluates whether adding Hayman sutures in the conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique reduces intraoperative blood loss and improves outcomes
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Apr 2026
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 2, 2026
CompletedStudy Start
First participant enrolled
April 5, 2026
CompletedFirst Posted
Study publicly available on registry
April 9, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2026
April 9, 2026
April 1, 2026
9 months
April 2, 2026
April 2, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Intra-operative estimated blood loss
During operation
Study Arms (2)
Kasr Al-Ainy Technique Alone
ACTIVE COMPARATORKasr Al-Ainy Technique + Hayman Sutures
EXPERIMENTALInterventions
1. Vascular Ligation: Bilateral uterine artery tying at high and low levels. 2. Compression Sutures: Anterior and posterior cervicovaginal stitches for hemostasis. 3. Segmental Resection: Excision of invaded myometrium and placental tissue. 4. Dual-Layer Repair: Myometrial approximation followed by reinforcing imbricating sutures. 5. Final Hemostasis: Confirmation of bleeding control prior to abdominal closure.
1. Vascular Ligation: Bilateral uterine artery tying at high and low levels. 2. Compression Sutures: Anterior and posterior cervicovaginal stitches for hemostasis. 3. Segmental Resection: Excision of invaded myometrium and placental tissue. 4. Dual-Layer Repair: Myometrial approximation followed by reinforcing imbricating sutures. 5. Final Hemostasis: Confirmation of bleeding control prior to abdominal closure. 6. Application of Hayman vertical compression sutures
Eligibility Criteria
You may qualify if:
- Age 18-40 years
- Antenatal PAS diagnosis confirmed by TAS/TVS/Doppler
- Eligible for conservative Kasr Al-Ainy surgery
- Singleton pregnancy
- Written informed consent
You may not qualify if:
- Multiple pregnancy
- Uterine fibroids
- Previous cesarean myomectomy
- Cervical accreta
- Extensive parametrial or bladder invasion requiring hysterectomy
- Known coagulopathy or uncorrected bleeding disorder.
- Severe medical comorbidities rendering the patient unfit for major surgery under general anesthesia (e.g., severe cardiac or pulmonary disease)
- Medical disorders as HTN and DM
- Patient refusal
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Emad Salah, M.D.
Cairo University
- PRINCIPAL INVESTIGATOR
Mona Sedik, M.D.
Cairo University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer of Obstetrics and Gynecology
Study Record Dates
First Submitted
April 2, 2026
First Posted
April 9, 2026
Study Start
April 5, 2026
Primary Completion (Estimated)
December 31, 2026
Study Completion (Estimated)
December 31, 2026
Last Updated
April 9, 2026
Record last verified: 2026-04