OST and MORES in Male Osteoporosis

NCT07518212 | Active Not Recruiting

• 1 other identifier: Male osteoporosis
• Study Type: observational
• Target: 140
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to compare the Male Osteoporosis Risk Score and the Osteoporosis Self-Assessment Tool with the gold standard DEXA in determining the risk of osteoporosis in the lumbar and femoral regions in male individuals in the Turkish population, and to investigate their sensitivity and specificity in the first stage of screening for the detection of male osteoporosis.

Conditions

Male Osteoporosis

Keywords

male ostoporosis; OST; MORES; osteoporosis risk estimation

Outcome Measures

Primary Outcomes (3)

• Dual energy Xray Absorptiometry (DEXA)

  DEXA measures bone mineral density (BMD; g/cm2) based on the scanned bone area. T and Z scores are used to interpret DEXA results. The T score indicates how many standard deviations below or above the average BMD measurements of a patient of the same gender and younger adults. The T score should be used for the diagnosis of osteoporosis in postmenopausal women and men over 50 years of age. The Z score indicates how many standard deviations below or above the average BMD measurements of the same gender and age. The Z score should be used for the diagnosis of osteoporosis in premenopausal women and men under 50 years of age. According to the World Health Organization's definition of bone mineral density: * A T score between -1 and -2.5 SD indicates osteopenia. * A T score below -2.5 SD indicates osteoporosis. * A T score below -2.5 SD accompanied by a fragility fracture(s) indicates severe osteoporosis. • A Z-score of -2.0 SD or lower is defined as "below the expected range for age,"

  January 2021-January 2024

• MORES

  The Male Osteoporosis Risk Prediction Score uses age, weight, and history of chronic obstructive pulmonary disease (COPD) to classify the risk of osteoporosis in men aged 50 and older. Values of 6 or higher are the threshold for screening.

  January 2021-January 2024

• OST

  The Osteoporosis Self-Assessment Tool (OSA) screening program is used to improve osteoporosis screening in patients. The main tool of this screening program is the OS, a risk formula based on age and weight. OS has proven to be a reliable screening tool for osteoporosis in both female and male populations. The OS score is calculated using the formula: OST Score = \[Weight (kg) - Age\] x 0.2. Osteoporosis risk: * High risk: -20 to -4 for women, -20 to -1 for men * Moderate risk: -4 to -1 for women, -1 to 4 for men * Low risk: -1 to 20 for women, -4 to 20 for men

  January 2021-January 2024

Study Arms (1)

male osteoporosis group

Eligibility Criteria

• Age: 50 Years - 75 Years
• Gender Eligibility Details: Cisgender male participant
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This study will be conducted retrospectively at the Physical Medicine and Rehabilitation Clinic of Kayseri City Hospital between January 2024 and January 2025. This study will include male patients aged 50-75 who underwent osteoporosis screening with DEXA at the Kayseri City Hospital Physical Medicine and Rehabilitation outpatient clinics between January 2021 and January 2024.

You may not qualify if:

• Patients younger than 50 or older than 75 years of age
• Patients with secondary osteoporosis
• Female patients
• Patients with uncontrolled severe comorbid conditions
• Patients with a history of pathological fractures

Sponsors & Collaborators

• Kayseri City Hospital: lead

Study Sites (1)

Kayseri City Education and Research Hospital

Kayseri, Kayseri, 38050, Turkey (Türkiye)

Location

Study Officials

• Fatma Gül Ülkü Demir, MD

  Kayseri City Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: February 4, 2026
• First Posted: April 8, 2026
• Study Start: February 4, 2026
• Primary Completion: July 1, 2026
• Study Completion (Estimated): September 15, 2026
• Last Updated: April 8, 2026

Record last verified: 2026-04

Locations

TU (1)