Ventricular Arrhythmias in Acute Myocardial Infarction

NCT07517523 | Recruiting

• 1 other identifier: ADVERSE MI STUDY
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 8

Brief Summary

Ventricular arrhythmias are a serious complication of myocardial infarction. The aim of this study is to provide reliable data on the management and mortality associated with ventricular arrhythmia in the setting of acute myocardial infarction.

Conditions

Ventricular Arrhythmia; Acute Myocardial Infarction (AMI)

Keywords

ST-segment elevation myocardial infarction; non-ST-segment elevation myocardial infarction; ventricular fibrillation; ventricular tachycardia; cardiac arrest; implantable cardioverter defibrillator

Outcome Measures

Primary Outcomes (1)

• Post-discharge mortality

  through study completion, an average of 2 years

Secondary Outcomes (9)

• Baseline demographic and clinical characteristics at inclusion

  At baseline

• Number of participants fot each type of myocardial infarction

  At baseline

• Number of participants with each ventricular arrhythmia characteristic and management strategy during index hospitalization

  At baseline

• In-hospital mortality

  From admission until the date of death or hospital discharge, whichever came first, assessed up to 28 days

• Number of participants with wearable cardioverter-defibrillator utilization

  At baseline

Study Arms (1)

Ventricular arrhythmia

patients who developed a sustained ventricular arrhythmia (ventricular tachycardia or ventricular fibrillation) during the acute phase of myocardial infarction, i.e., from infarct onset to hospital discharge

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All included individuals will be consecutive patients who developed a sustained ventricular arrhythmia during the acute phase of a myocardial infarction between January 1, 2012, and April 14, 2024.

You may qualify if:

• ≥ 18 years
• Acute myocardial infarction
• Sustained ventricular arrhythmia (ventricular tachycardia or ventricular fibrillation) at the acute phase of an acute myocardial infarction (before hospital discharge)
• Between January 1, 2012 and April 14, 2024

You may not qualify if:

• None

Sponsors & Collaborators

• Poitiers University Hospital: lead

Study Sites (8)

University hospital of Caen

Caen, France

RECRUITING

University hospital of Dijon

Dijon, France

RECRUITING

University hospital of Grenoble

Grenoble, France

RECRUITING

Hopital Européen Georges Pompidou

Paris, France

RECRUITING

Hospital of Pau

Pau, France

RECRUITING

University hospital of Poitiers

Poitiers, France

RECRUITING

University hospital of Saint Etienne

Saint-Etienne, France

RECRUITING

University hospital of Tours

Tours, France

RECRUITING

MeSH Terms

Conditions

ST Elevation Myocardial Infarction; Ventricular Fibrillation; Tachycardia, Ventricular; Heart Arrest

Condition Hierarchy (Ancestors)

Myocardial Infarction; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis; Arrhythmias, Cardiac; Tachycardia; Cardiac Conduction System Disease

Study Officials

• Rodrigue Garcia, MD; PhD

  Cardiology department and CIC 1402; University Hospital of Poitiers

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Véronique Le Marcis

CONTACT

+33 5 49444084; veronique.le-marcis@chu-poitiers.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 11, 2026
• First Posted: April 8, 2026
• Study Start: June 20, 2025
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): October 1, 2027
• Last Updated: May 28, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

FR (8)