NCT07513467|Not Yet Recruiting
3T Magnetic Resonance Neurography
3T MRN
High-resolution MR Neurography Evaluation of the Cervical Spine at 3 Tesla
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3T MRN
High-resolution MR Neurography Evaluation of the Cervical Spine at 3 Tesla
Sponsor study identifier
observational
30
1 country
1
Study Start
June 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
April 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
June 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
The goal of this observational study is to evaluate whether optimized high-resolution MRI can better visualize very fine nerves in the cervical spine and neck region compared to standard MRI. The main question it aims to answer is: Can high-resolution MRI reliably show small nerves and potentially detect their injuries or diseases that are often invisible on conventional MRI scans? Participants will come once to Balgrist University Hospital for a one-hour visit. They will fill out a questionnaire and have a single 30-minute MRI scan of the cervical spine without contrast.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 20, 2026
Actual (reported)April 7, 2026
Actual (reported)June 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
April 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
June 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Proportion of visible small-caliber nerve segments
Visibility of small-caliber cervical nerves (phrenic, spinal accessory, dorsal scapular, vagus nerve) per segment (proximal, midsegment, distal) on both sides (left/right) per volunteer. Two board-certified radiologists with experience in MR Neurography will independently determine visibility (binary score: 0 = not visible, 1 = visible). Visibility is defined as continuous depiction of the nerve segment over its entire length with signal intensity clearly distinguishable from background tissue.
Within 12 weeks after MRI acquisition during radiological readout
Image quality score across different acceleration factors
Within 12 weeks after MRI acquisition during radiological readout
Inter-reader agreement for visibility and image quality
Within 12 weeks after MRI acquisition during radiological readout
Frequency of anatomic variants
Within 12 weeks after MRI acquisition during radiological readout
Clinical standard three-dimensional magnetic resonance neurography sequences with high spatial resolution
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Healthy volunteers
Balgrist University Hospital
Zurich, 8008, Switzerland
First Submitted
March 20, 2026
First Posted
April 7, 2026
Study Start
June 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
April 2028
EstimatedNormative Values For Physical Fitness
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Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
June 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
April 7, 2026
Record last verified: 2026-03
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Source: ClinicalTrials.gov.
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