NCT07511751

Brief Summary

This study aims to compare the effectiveness of dry needling, extracorporeal shock wave therapy (ESWT), and pulsed radiofrequency (PRF) in patients with chronic musculoskeletal pain. The primary outcomes include pain intensity and functional status. Patients will be randomly assigned to different treatment groups, and outcomes will be evaluated before and after the interventions. The results of this study are expected to contribute to determining the most effective treatment method for pain management.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
10mo left

Started Mar 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress16%
Mar 2026Mar 2027

Study Start

First participant enrolled

March 10, 2026

Completed
20 days until next milestone

First Submitted

Initial submission to the registry

March 30, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 6, 2026

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 10, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 10, 2027

Last Updated

April 15, 2026

Status Verified

April 1, 2026

Enrollment Period

1 year

First QC Date

March 30, 2026

Last Update Submit

April 11, 2026

Conditions

Myofascial Pain Syndrome

Keywords

myofascial pain syndromedry needlingESWTpulsed radiofrequencypain

Outcome Measures

Primary Outcomes (1)

  • Pain Intensity

    Pain intensity will be assessed using the Numeric Rating Scale(NRS). Pain intensity will be assessed using the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate greater pain severity.

    Baseline, 1 month, and 3 months after treatment

Secondary Outcomes (3)

  • Pressure Pain Threshold

    Baseline, 1 month, and 3 months after treatment

  • Neck Disability Index (NDI)

    Baseline, 1 month, and 3 months after treatment

  • Quality of Life (SF-12

    Baseline, 1 month, and 3 months after treatment

Study Arms (3)

Dry Needling Group

EXPERIMENTAL

Patients receiving dry needling treatment.

Procedure: Dry Needling

ESWT Group

EXPERIMENTAL

Patients receiving extracorporeal shock wave therapy (ESWT)

Procedure: Extracorporeal Shock Wave Therapy

PRF Group

EXPERIMENTAL

Patients receiving pulsed radiofrequency (PRF) treatment.

Procedure: Pulsed radiofrequency(PRF)

Interventions

Dry NeedlingPROCEDURE

Dry needling applied to myofascial trigger points

Dry Needling Group
Extracorporeal Shock Wave TherapyPROCEDURE

Extracorporeal shock wave therapy applied to the painful area

ESWT Group
Pulsed radiofrequency(PRF)PROCEDURE

Pulsed radiofrequency applied to the target area for the treatment of myofascial pain syndrome

PRF Group

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age between 18 and 65 years
  • Clinically diagnosed myofascial pain syndrome
  • Back pain lasting at least 3 months
  • Failure to respond to conservative treatments

You may not qualify if:

  • History of cervical surgery or cervical disc pathology
  • Fibromyalgia
  • Shoulder pathologies
  • Coagulation disorders or use of anticoagulant therapy
  • Infection, malignancy, or inflammatory spinal diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sakarya Training and Research Hospital

Adapazarı, Sakarya, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Myofascial Pain SyndromesPain

Interventions

Dry NeedlingExtracorporeal Shockwave TherapyPulsed Radiofrequency Treatment

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Complementary TherapiesTherapeuticsPhysical Therapy ModalitiesUltrasonic TherapyDiathermyHyperthermia, InducedRehabilitationElectric Stimulation TherapyRadiofrequency Therapy

Study Officials

  • KEMAL NAS, MD, Professor

    Sakarya University Training and Research Hospital, Department of Algology

    PRINCIPAL INVESTIGATOR

  • RIDVAN ISIK, MD

    Sakarya University Training and Research Hospital, Department of Algology

    STUDY CHAIR

Central Study Contacts

AYSENUR IMAMOGLU BABA, MD,Resident

CONTACT

+905437866097aysenurimamoglub@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants will be assigned to three parallel groups receiving dry needling, extracorporeal shock wave therapy (ESWT), or pulsed radiofrequency (PRF), respectively.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Associate Professor, Department of Anesthesiology and Reanimation

Study Record Dates

First Submitted

March 30, 2026

First Posted

April 6, 2026

Study Start

March 10, 2026

Primary Completion (Estimated)

March 10, 2027

Study Completion (Estimated)

March 10, 2027

Last Updated

April 15, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)