NCT07508475

Brief Summary

A Randomized Controlled Clinical Study aims for Clinical Assessment of CAD/CAM Fabricated Lithium-Disilicate overlay in comparison to Lithium-disilicate Endocrowns for Restoration of Endodontically Treated Teeth.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2023

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
14 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 15, 2024

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

March 9, 2026

Completed
24 days until next milestone

First Posted

Study publicly available on registry

April 2, 2026

Completed
Last Updated

April 2, 2026

Status Verified

March 1, 2026

Enrollment Period

7 months

First QC Date

March 9, 2026

Last Update Submit

March 31, 2026

Conditions

Nonvital Tooth

Keywords

NonvitalOverlayEndocrownCeramics

Outcome Measures

Primary Outcomes (1)

  • marginal adaptations

    Marginal adaptation will be evaluated using Modified United States Public Health Service (USPHS) criteria by two calibrated independent examiners. Scores will be recorded as Alpha, Bravo, or Charlie based on marginal integrity.

    Baseline, 5 months, 10 months, 15 months, and 20 months

Secondary Outcomes (2)

  • marginal discoloration

    Baseline, 5, 10, 15, and 20 months

  • patient satisfaction

    20 months

Study Arms (2)

lithium disilicate endocrown

ACTIVE COMPARATOR
Other: lithium disilicate overlays

overlay

ACTIVE COMPARATOR
Other: lithium disilicate overlays

Interventions

lithium disilicate overlaysOTHER

indirect partial coverage restoration that cover mainly the occlusal surface of posterior teeth

Also known as: occlusal veneer ,ceramic partial coverage
lithium disilicate endocrownoverlay

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with endodontically treated teeth indicated to ceramic Endocrowns.
  • Patients with endodontically treated teeth indicated to ceramic overlays.
  • Physically and psychologically able to tolerate conventional restorative procedures.
  • Have no active periodontal or periapical diseases.
  • Maintenance of good oral hygiene.
  • Willing to return for follow-up examinations and evaluation.

You may not qualify if:

  • Patients in the growth stage with partially erupted teeth.
  • Patients with para-functional habits.
  • Patients with defective endodontic treatment.
  • Patients with poor oral hygiene and motivation.
  • Psychiatric problems or unrealistic expectations.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry Cairo University

Cairo, Cairo Governorate, 12567, Egypt

Location

MeSH Terms

Conditions

Tooth, Nonvital

Condition Hierarchy (Ancestors)

Dental Pulp DiseasesTooth DiseasesStomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer assisstant

Study Record Dates

First Submitted

March 9, 2026

First Posted

April 2, 2026

Study Start

August 1, 2023

Primary Completion

March 1, 2024

Study Completion

March 15, 2024

Last Updated

April 2, 2026

Record last verified: 2026-03

Locations

EG(1)