Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Block With Dexmetomidine vs Dexmethasone
Comparison of Mean Duration of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving US Transversus Abdominis Plane Block (TAP) With Bupivacaine and Dexmetomidine vs Bupivacaine nd Dexmethasone
1 other identifier
interventional
60
1 country
1
Brief Summary
Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding drugs to local anesthetic regimen
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_4
Started Mar 2026
Shorter than P25 for phase_4
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 27, 2026
CompletedStudy Start
First participant enrolled
March 27, 2026
CompletedFirst Posted
Study publicly available on registry
April 2, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 26, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 26, 2026
April 2, 2026
March 1, 2026
3 months
March 27, 2026
March 27, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Resuce analgesia
Time in the post operative period when patient first demands rescues analgesia will be noted in minutes
Study Arms (2)
Dexmedetomidine
ACTIVE COMPARATORDexamethasone
ACTIVE COMPARATORInterventions
20 ml 0.25% Bupivacaine along with 0.5 Mcg/kg of Dexmedetomidine will be given in TAPP block bilaterally
20 ml 0.25% Bupivacaine along with 4 mg of Dexamethasone will be given in TAPP block bilaterally
Eligibility Criteria
You may qualify if:
- ASA I and ASA II BMI 25-35 kg/m2 Lower abdominal surgeries below L2-L3 leves
You may not qualify if:
- Infection at block site Coagulopathy Antiplatelet
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Pakistan Institute of Medical Sciences Islamabad
Islamabad, Federal, 44000, Pakistan
Related Publications (1)
Sobhy YS, Gadalla RR, Nofal WH, Saleh MAE, Abdou KM. A comparative study between the use of dexmedetomidine .vs dexamethasone as adjuvants to bupivacaine in ultrasound-guided transversus abdominis plane block for postoperative pain relief in patients undergoing lower abdominal surgeries. Anaesth. pain intensive care 2022;26(5):681-688
BACKGROUND
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Central Study Contacts
Department of Anesthesia Principal Investigator
CONTACT
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
March 27, 2026
First Posted
April 2, 2026
Study Start
March 27, 2026
Primary Completion (Estimated)
June 26, 2026
Study Completion (Estimated)
June 26, 2026
Last Updated
April 2, 2026
Record last verified: 2026-03
Data Sharing
- IPD Sharing
- Will not share
Hospital Ethical Committe doesnt allow