Association Between Fatigue Severity and Health-Related Quality of Life in Individuals With Stroke

NCT07498114 | Completed

• 1 other identifier: uskudarunivstroke
• Study Type: observational
• Target: 53
• Locations: 1 country
• Sites: 1

Brief Summary

This observational cross-sectional study aims to examine the association between fatigue severity and health-related quality of life in individuals with stroke. Fatigue severity will be assessed using the Fatigue Severity Scale (FSS), and quality of life will be evaluated using the Nottingham Health Profile (NHP). The primary analysis will investigate the relationship between FSS total score and NHP total score and domain scores.

Conditions

Stroke; Quality of Life; Post Stroke Fatigue

Outcome Measures

Primary Outcomes (2)

• Fatigue Severity Scale

  Fatigue Severity Scale (FSS) is a 9-item self-report questionnaire used to assess the severity of fatigue and its impact on daily functioning. Each item is scored on a 7-point Likert scale (1-7), with higher scores indicating greater fatigue severity. The FSS is a reliable and widely used measure in clinical and research settings.

  Single assessment at enrollment (baseline)

• Nottingham Health Profile

  Nottingham Health Profile (NHP) is a self-reported questionnaire used to assess perceived health status and quality of life. It consists of 38 items covering six domains: physical mobility, pain, sleep, energy, social isolation, and emotional reactions. Higher scores indicate poorer health status.

  Single assessment at enrollment (baseline)

Study Arms (1)

Individuals with stroke meeting eligibility criteria.

No interventions will be administered

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

unit/community stroke follow-up\].

You may qualify if:

• Time since stroke: ≥ \[3\] months
• Able to understand and complete questionnaires (with/without assistance)
• Provides informed consent

Sponsors & Collaborators

• Uskudar University: lead

Study Sites (1)

Üsküdar Üniversitesi

Istanbul, Turkey (Türkiye)

Location

Related Publications (2)

• Ponchel A, Bombois S, Bordet R, Henon H. Factors Associated with Poststroke Fatigue: A Systematic Review. Stroke Res Treat. 2015;2015:347920. doi: 10.1155/2015/347920. Epub 2015 May 25.

  PMID: 26101691 RESULT

• Tang WK, Lu JY, Chen YK, Mok VC, Ungvari GS, Wong KS. Is fatigue associated with short-term health-related quality of life in stroke? Arch Phys Med Rehabil. 2010 Oct;91(10):1511-5. doi: 10.1016/j.apmr.2010.06.026.

  PMID: 20875507 RESULT

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asst. Prof.

Study Record Dates

• First Submitted: March 23, 2026
• First Posted: March 27, 2026
• Study Start: March 5, 2026
• Primary Completion: March 25, 2026
• Study Completion: March 25, 2026
• Last Updated: March 30, 2026

Record last verified: 2026-03

Locations

TU (1)