Effects of Diabetic Educational Intervention and Dietary Supplements on Blood Glucose, Lipid Profile Levels, Body Mass Index, and Pain Management Among Adult Individuals With Painful Diabetic Peripheral Neuropathy.

NCT07496619 | Completed DMC

• 1 other identifier: MOH Jordan (No: 99011)
• Study Type: interventional
• Target: 62
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study was to assess the effects of a diabetes education intervention with cinnamon supplement on blood glucose, lipid profile, body mass index (BMI), and peripheral neuropathy pain in adults with type 2 diabetes. A quasi-experimental pretest/post-test design was employed, with data collected from March to August 2022 at endocrinology clinics at the Ministry of Health Clinics in Jordan. The study included 62 adults with PDPN, who were randomly assigned to either an experimental or a control group. Data were collected at baseline, 3 months, and 6 months using clinical and biochemical assessments and the Numeric Rating Scale for pain.

Conditions

Pain; Glucose Levels; Low-density Lipoprotein Lipid Composition; Cholesterol (Total and HDL)

Keywords

Diabetic educational intervention; Painful diabetic peripheral neuropathy; Cinnamon supplementation; Insulin resistance; Blood glucose; Lipid profile.

Outcome Measures

Primary Outcomes (4)

• Lipid Profile Levels

  Lipid Profile Levels (Lipid profile levels (Total, HDL, LDL cholesterol, and Triglycerides) are primarily measured in milligrams per deciliter (mg/dL)

  up to 4 months

• Blood Glucose

  Fasting blood glucose (FBG) (mg/dL) + Glycosylated hemoglobin (HbA1C) (%)

  up to 4 months

• Body Mass Index

  Body Mass Index using (Weight in Kg/Height in m2). Weight and height will be combined to report BMI in kg/m\^2

  up to 4 months

• Pain levels

  Pain levels using Pain numeric Rating Scale form 0 to 10

  up to 4 months

Study Arms (1)

Diabetic Educational Intervention and Dietary Supplements

EXPERIMENTAL

The structured educational intervention and dietary supplementation model was specifically designed for adult patients with painful diabetic peripheral neuropathy. It was developed by the authors based on a review of relevant literature and aligned with the self-management efficacy philosophy. The model covered the following topics: information about DM and PDPN, diabetes complications, prevention through self-car, self-efficacy towards the management of PDPN, diabetes self-care activities include medication administration, blood glucose self-analysis, and foot care, compliance and lifestyle modification such as a healthy diet adapted to the diabetic individual, physical exercise, quitting smoking, regular follow-up, and weight control, self-efficacy towards the management of hyperglycemia and hypoglycemia, pain management, and information about cinnamon supplementation.

Other: Diabetic Educational Intervention and Dietary Supplements

Interventions

Diabetic Educational Intervention and Dietary Supplements OTHER

The structured educational intervention and dietary supplementation model was specifically designed for adult patients with painful diabetic peripheral neuropathy. It was developed by the authors based on a review of relevant literature and aligned with the self-management efficacy philosophy. The model covered the following topics: information about DM and PDPN, diabetes complications, prevention through self-car, self-efficacy towards the management of PDPN, diabetes self-care activities include medication administration, blood glucose self-analysis, and foot care, compliance and lifestyle modification such as a healthy diet adapted to the diabetic individual, physical exercise, quitting smoking, regular follow-up, and weight control, self-efficacy towards the management of hyperglycemia and hypoglycemia, pain management, and information about cinnamon supplementation.

Diabetic Educational Intervention and Dietary Supplements

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• adult patients (aged 18 years or older)
• diagnosed with painful diabetic peripheral neuropathy at Ministry of Health Clinics in 2021.

You may not qualify if:

• Participants with chronic conditions such as chronic kidney disease (CKD).
• Hypertension patients.
• Cardiovascular disease (CVD).
• Other coexisting medical issues, including cognitive impairment or sensory impairments (e.g., reading or hearing difficulties).
• Individuals who had received treatments that could influence blood glucose levels or pain perception during basic insulin and peripheral neuropathy (PNP) therapy (such as glucocorticoids, weight-loss medications, or therapies related to vitamin B12 or iron supplementation).

Sponsors & Collaborators

• Al-Quds University: lead

Study Sites (1)

Al-Quds University

East Jerusalem, Abu Dies, Palestinian Territories

Location

MeSH Terms

Conditions

Pain; Insulin Resistance

Interventions

Dietary Supplements

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: March 16, 2026
• First Posted: March 27, 2026
• Study Start: March 1, 2022
• Primary Completion: August 1, 2022
• Study Completion: August 1, 2022
• Last Updated: March 31, 2026

Record last verified: 2026-03

Locations

PA (1)