NCT07493733

Brief Summary

-Comparison of MPTA on both Full-leg Standing and Rosenberg Radiographs .

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
49

participants targeted

Target at P25-P50 for all trials

Timeline
24mo left

Started Oct 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 17, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 25, 2026

Completed
6 months until next milestone

Study Start

First participant enrolled

October 1, 2026

Expected
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2028

2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2028

Last Updated

March 25, 2026

Status Verified

March 1, 2026

Enrollment Period

1.8 years

First QC Date

March 17, 2026

Last Update Submit

March 21, 2026

Conditions

Medial Proximal Tibial Angle

Outcome Measures

Primary Outcomes (1)

  • Difference in medial proximal tibial angle (MPTA) measurments in both the Rosenberg view and full-leg standing radiographic position

    Baseline

Interventions

X-rayDEVICE

comparing of MPTA on full standing and rosenberg views

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Outpatient clinics and inpatient ward of Orthopedics \& Trauma Surgery Department , Asyut University Hospitals , Faculty of Medicine

You may qualify if:

  • All patients were screened for medial compartment OA of either the left or right knee joint.
  • Availability of preoperative full-length standing radiograph and Rosenberg view.
  • Completeness of patient records .
  • Patient consent

You may not qualify if:

  • Insufficient patient records .
  • Previous ligamentous surgery or osteotomies .
  • Known neuromuscular or metabolic disorder .
  • Absence of a radiographic reference ball.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (10)

  • Ogata K, Yoshii I, Kawamura H, Miura H, Arizono T, Sugioka Y. Standing radiographs cannot determine the correction in high tibial osteotomy. J Bone Joint Surg Br. 1991 Nov;73(6):927-31. doi: 10.1302/0301-620X.73B6.1955438.

    PMID: 1955438BACKGROUND

  • [9] Deep K, Eachempati KK, Apsingi S. The dynamic nature of alignment and variations in normal knees. Bone Joint Lett J 2015;97-B(4):498-502. https://doi.org/ 10.1302/0301-620X.97B4.33740.

    BACKGROUND

  • Palmer J, Getgood A, Lobenhoffer P, Nakamura R, Monk P. Medial opening wedge high tibial osteotomy for the treatment of medial unicompartmental knee osteoarthritis: A state-of-the-art review. J ISAKOS. 2024 Feb;9(1):39-52. doi: 10.1016/j.jisako.2023.10.004. Epub 2023 Oct 13.

    PMID: 37839705BACKGROUND

  • [7] Dugdale TW, Noyes FR, Styer D. Preoperative planning for high tibial osteotomy. The effect of lateral tibiofemoral separation and tibiofemoral length. Clin Orthop Relat Res 1992;274:248-64.

    BACKGROUND

  • [6] Yasuda K, Majima T, Tsuchida T, Kaneda K. A ten- to 15-year follow-up observation of high tibial osteotomy in medial compartment osteoarthrosis. Clin Orthop Relat Res 1992;282:186-95.

    BACKGROUND

  • [5] Hernigou P, Medevielle D, Debeyre J, Goutallier D. Proximal tibial osteotomy for osteoarthritis with varus deformity. A ten to thirteen-year follow-up study. J Bone Joint Surg Am 1987;69(3):332-54.

    BACKGROUND

  • Coventry MB, Ilstrup DM, Wallrichs SL. Proximal tibial osteotomy. A critical long-term study of eighty-seven cases. J Bone Joint Surg Am. 1993 Feb;75(2):196-201. doi: 10.2106/00004623-199302000-00006.

    PMID: 8423180BACKGROUND

  • COVENTRY MB. OSTEOTOMY OF THE UPPER PORTION OF THE TIBIA FOR DEGENERATIVE ARTHRITIS OF THE KNEE. A PRELIMINARY REPORT. J Bone Joint Surg Am. 1965 Jul;47:984-90. No abstract available.

    PMID: 14318636BACKGROUND

  • [1] Ayet CAB, Mancino F, Lim YP, Qian K, Jacob G, Parker DA. Satisfactory 10-year survivorship of medial opening wedge high tibial osteotomy for isolated medial compartment osteoarthritis and varus alignment: an analysis from a high-volume institution. Knee Surg Sports Traumatol Arthrosc 2025 May;33(5):1804-14. https://doi.org/10.1002/ksa.12633. Published online February 20.

    BACKGROUND

  • Gkekas NK, Komnos GA, Mylonas T, Chalatsis G, Koutalos AA, Hantes ME. Medial open wedge high tibial osteotomy is a viable option in young patients with advanced arthritis in a long-term follow-up. Knee Surg Sports Traumatol Arthrosc. 2025 Mar;33(3):1025-1032. doi: 10.1002/ksa.12469. Epub 2024 Sep 18.

    PMID: 39290201BACKGROUND

MeSH Terms

Interventions

Diagnostic Imaging

Intervention Hierarchy (Ancestors)

Diagnostic Techniques and ProceduresDiagnosis

Central Study Contacts

Ahmed Gadelkarem Farrag, Resident Doctor

CONTACT

+20 01009372187agad6126@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Invistegator

Study Record Dates

First Submitted

March 17, 2026

First Posted

March 25, 2026

Study Start (Estimated)

October 1, 2026

Primary Completion (Estimated)

August 1, 2028

Study Completion (Estimated)

October 1, 2028

Last Updated

March 25, 2026

Record last verified: 2026-03