NCT07488234

Brief Summary

Glaucoma is a leading cause of irreversible blindness worldwide, with a higher burden in low- and middle-income countries such as Nepal, where public awareness and treatment adherence remain poor. Lifelong adherence to treatment is important to prevent disease progression but still non adherence remains common. This is a mixed method study which aims to evaluate the effectiveness of structured glaucoma awareness program in improving treatment adherence among glaucoma patients attending a tertiary eye hospital in Nepal. Quantitative assessment will measure changes in treatment adherence using Medication Adherence Scale at baseline and three months post intervention. A qualitative component will explore participants' perceptions of glaucoma program and suggestions for improvement through semi-structured interviews.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
12mo left

Started Apr 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress12%
Apr 2026Jun 2027

First Submitted

Initial submission to the registry

December 30, 2025

Completed
3 months until next milestone

First Posted

Study publicly available on registry

March 23, 2026

Completed
9 days until next milestone

Study Start

First participant enrolled

April 1, 2026

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2027

Expected
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2027

Last Updated

March 23, 2026

Status Verified

March 1, 2026

Enrollment Period

1 year

First QC Date

December 30, 2025

Last Update Submit

March 18, 2026

Conditions

Glaucoma

Keywords

GlaucomaGlaucoma awareness programTreatment adherencePatient educationNepal

Outcome Measures

Primary Outcomes (1)

  • Treatment adherence scores

    Treatment adherence will be assessed using Glaucoma Treatment Compliance Assessment Tool- Short Form(GTCAT-S). Treatment adherence will be assessed using the Glaucoma Treatment Compliance Assessment Tool-Short Form (GTCAT-S), a validated self-administered questionnaire designed to evaluate adherence behavior, beliefs, and barriers among glaucoma patients. Approval for the use of GTCAT-S in this study has been obtained from the GTCAT development team. Scale Details: * Each item is scored on a 5-point Likert scale: 1 = Disagree a lot to 5 = Agree a lot * Patients classified * Low adherence: \<75% * High adherence: ≥75% * Direction: Higher scores indicate better treatment adherence

    10 months

Secondary Outcomes (1)

  • Participants' perceptions of the glaucoma awareness program assessed using semi-structured interview guide

    3 months post-intervention

Study Arms (1)

Glaucoma awareness

EXPERIMENTAL

Glaucoma awareness educational package: Educational session, information leaflets, interactive discussions

Other: Glaucoma awareness and patient education program

Interventions

Glaucoma awareness and patient education programOTHER

Glaucoma awareness educational package: Educational session, information leaflets, interactive discussions. This study involves a behavioral/educational intervention only. No drugs, devices, or procedures are introduced as part of the study intervention. Participants continue their routine standard-of-care glaucoma treatment as prescribed by their treating ophthalmologist. No investigational drugs or devices are used as part of this study. Participants continue their usual prescribed anti-glaucoma medications as part of routine clinical care. The study intervention consists solely of a structured educational and awareness program.

Glaucoma awareness

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed with glaucoma
  • Attending follow-up at the study hospital
  • Able to provide informed consent
  • Able to communicate in Nepali language

You may not qualify if:

  • Individuals with cognitive impairments; healthcare professionals; individuals who have participated in a formal glaucoma education program in the past year.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

GlaucomaTreatment Adherence and Compliance

Condition Hierarchy (Ancestors)

Ocular HypertensionEye DiseasesHealth BehaviorBehavior

Study Officials

  • Priya Adisesha Reddy

    Seva Canada Society

    STUDY DIRECTOR

Central Study Contacts

Dr. Deekshya Malla

CONTACT

+977 9851182007deekshyamalla@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 30, 2025

First Posted

March 23, 2026

Study Start

April 1, 2026

Primary Completion (Estimated)

April 1, 2027

Study Completion (Estimated)

June 1, 2027

Last Updated

March 23, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share