Assess Abdominal Aortic Diameter in Females

NCT07487961 | Recruiting

• 1 other identifier: 6251
• Study Type: observational
• Target: 652
• Locations: 1 country
• Sites: 1

Brief Summary

Female subjects aged 50 years or older will be enrolled. Biometric data (measurements) of the aorta and iliac vessels, demographic data, pathophysiological history, and data relating to menarche, pregnancy/infertility, and menopause will be collected. The aortic diameter measurement protocol will follow standard clinical practice. Measurements will be performed by placing the probe on an axis perpendicular to the aortic axis, manually positioning the calipers in the antero-posterior and lateral-lateral directions, recording both the outer-to-outer (OTO) and inner-to-inner (ITI) diameters. Additionally, the presence of thrombus and/or calcifications and the outer-to-outer (OTO) measurement of the common iliac arteries will be detected. Primary objective: Definition of the ultrasound diameter of the abdominal aorta in the female population. Secondary objective: Identification of any sex-specific risk factors associated with abdominal aortic disease (aneurysm) in the female population. Secondary objective: Identification of any sex-specific risk factors associated with abdominal aortic disease (atherosclerosis) in the female population.

Conditions

Aorta Disease; Aorta Aneurysm

Outcome Measures

Primary Outcomes (1)

• AP and LL (inner-to-inner and outer-to-outer) measurement in mm at ultrasound of the infrarenal aortic segment

  Association between medical history and the presence of abdominal aortic aneurysm, assessed in millimeters, through anteroposterior \[AP\] and laterolateral \[LL\] measurements of the infrarenal segment.

  baseline

Secondary Outcomes (1)

• association between anamnestic information and the presence of abdominal aortic atherosclerosis

  baseline

Eligibility Criteria

• Age: 50 Years+
• Gender Eligibility Details: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

general population

You may qualify if:

• female sex
• ≥ 50 YO

You may not qualify if:

• \< 50 years
• Previous diagnosis of abdominal/thoracic aneurysm disease
• Subjects who have previously undergone surgery (both open and endovascular) on the thoracic and/or abdominal aorta
• Presence of mental disability and/or inability to sign informed consent

Sponsors & Collaborators

• Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico: lead

Study Sites (1)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy

RECRUITING

MeSH Terms

Conditions

Aortic Diseases; Aortic Aneurysm

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Aneurysm

Central Study Contacts

CHIARA LOMAZZI, MD

CONTACT

+390255036670; chiara.lomazzi@policlinico.mi.it

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 6, 2026
• First Posted: March 23, 2026
• Study Start: September 29, 2025
• Primary Completion (Estimated): July 30, 2027
• Study Completion (Estimated): July 30, 2027
• Last Updated: March 27, 2026

Record last verified: 2026-03

Locations

IT (1)