Oxygenation in Posterior Stabilization Surgery

NCT07487324 | Not Yet Recruiting

• 1 other identifier: SAU-ANE-EG-01
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the effects of prone positioning on oxygenation, ventilation, and hemodynamic parameters in patients undergoing posterior stabilization surgery under general anesthesia. By comparing routine anesthesia and monitoring data obtained in the supine and prone positions, the study seeks to determine how positional changes influence respiratory mechanics and perioperative physiological stability.

Conditions

Oxygen; Oxygen Saturation

Keywords

oxygenation; Posterior Stabilization Surgery; Mechanical Ventilation Parameters; optic nerve sheath diamater

Outcome Measures

Primary Outcomes (1)

• Change in alveolar oxygenation between supine and prone positions

  The primary outcome of this study is to evaluate the difference in alveolar oxygenation between the supine and prone positions in patients undergoing posterior stabilization surgery. Arterial blood gas samples obtained during surgery will be used to compare oxygenation parameters measured in both positions and to assess the effect of positional change on oxygenation.

  within 20 minutes after anesthesia induction

Secondary Outcomes (1)

• Change in optic nerve sheath diameter between supine and prone positions

  intraoperatively

Study Arms (2)

group supine

Retrospective evaluation of routine intraoperative anesthesia and monitoring parameters recorded while patients were in the supine position before prone positioning.

Other: blood gase

group prone

Retrospective evaluation of routine intraoperative anesthesia and monitoring parameters recorded after patients were placed in the prone position during posterior stabilization surgery.

Other: blood gase

Interventions

blood gase OTHER

Arterial blood gas samples will be obtained from patients, and alveolar oxygenation ratios will be compared between the supine and prone positions.

group prone; group supine

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

the study population consists of women reproductive age (18-80 years ) who are sheduled to undergo Posterior Stabilization Surgery under general anesthesia.

You may qualify if:

• Patients aged 18 to 75 years Patients classified as ASA physical status I, II, or III according to the American Society of Anesthesiologists Patients undergoing posterior stabilization surgery Patients who voluntarily agreed to participate in the study Patients with a body mass index (BMI) \<35 kg/m² Patients followed with a standard mechanical ventilation procedure

You may not qualify if:

• \- ASA 4 olarak değerlendirilenler
• Anestezik ajan alerjisi olanlar
• Kanama diatezi bozukluğu olanlar
• Cerrahi süresi 3 saatin üstünde olanlar
• Bilinen ileri akciğer hastalığı olanlar (intertisyel akciğer hastalığı, ileri düzey KOAH, ileri düzey astım vb)
• VKI≥35 olanlar
• Obstrüktif uyku apne sendromu tanısı olanlar
• Toraks deformitesi olanlar
• Ciddi kalp yetmezliği öyküsü olanlar (EF\<30)
• Şiddetli anemi öyküsü olanlar (Hg\<8 mg/dl)
• Cerrahi operasyon sırasında kan transfüzyonu ihtiyacı olan hastalar

Sponsors & Collaborators

• Sakarya University: lead

Study Sites (1)

Sakarya Universt

Sakarya, Karabük Province, 78000, Turkey (Türkiye)

Location

Related Publications (1)

• Radstrom M, Loswick AC, Bengtsson JP. Respiratory effects of the kneeling prone position for low back surgery. Eur J Anaesthesiol. 2004 Apr;21(4):279-83. doi: 10.1017/s0265021504004053.

  PMID: 15109190 RESULT

MeSH Terms

Interventions

Blood Gas Analysis

Intervention Hierarchy (Ancestors)

Blood Chemical Analysis; Clinical Chemistry Tests; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Respiratory Function Tests; Diagnostic Techniques, Respiratory System; Investigative Techniques

Central Study Contacts

HAVVA KOCAYİĞİT, Associate Professor

CONTACT

905425950020; havvakocayigit@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: ANESTHESIOLOGIST

Study Record Dates

• First Submitted: March 17, 2026
• First Posted: March 23, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): October 15, 2026
• Study Completion (Estimated): November 15, 2026
• Last Updated: March 23, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)