NCT07485608

Brief Summary

The objective of this study is to assess the effectiveness of portable air filtration (PAF) for mitigating lead dust exposures and reducing childhood blood lead levels in older housing.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
4mo left

Started Dec 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress93%
Dec 2022Nov 2026

Study Start

First participant enrolled

December 1, 2022

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

May 2, 2023

Completed
2.9 years until next milestone

First Posted

Study publicly available on registry

March 20, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2026

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2026

Expected
Last Updated

March 20, 2026

Status Verified

March 1, 2026

Enrollment Period

3.7 years

First QC Date

May 2, 2023

Last Update Submit

March 17, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in blood lead level

    change in blood lead level (in ug/dL).

    After two months at the end of the intervention

Study Arms (1)

air filtration systems

EXPERIMENTAL

Portable air filtration units will be kept running in homes for two months.

Other: portable air filtration systems

Interventions

Two portable air filtration units placed in subjects' homes (one in child's bedroom and one in living room) will be kept running for two months.

air filtration systems

Eligibility Criteria

AgeUp to 7 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • child under seven years of age with BLL \>5 µg/dL,
  • child must reside in housing built before 1978, and
  • child must sleep at home during participation in the two month-long study.

You may not qualify if:

  • anything in child's health history that could affect the study results, or
  • any circumstance that could interfere with guardian's/parent's ability to consent and/or participate in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Michigan State University

East Lansing, Michigan, 48824, United States

RECRUITING

Central Study Contacts

Tuan Nguyen, BS

CONTACT

Masako Morishita, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

May 2, 2023

First Posted

March 20, 2026

Study Start

December 1, 2022

Primary Completion

July 31, 2026

Study Completion (Estimated)

November 30, 2026

Last Updated

March 20, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations