Effects of Circuit Training With and Without Upper and Lower Limb Resistance Training on Paroxysmal Nocturnal Dyspnea, Functional Capacity and Endurance in Post-CABG Patients
Sponsor study identifier
interventional
60
1 country
1
Study Start
July 5, 2025
Actual (reported)Primary Completion
August 20, 2025
Actual (reported)Study Completion
December 20, 2025
Actual (reported)This study aims to evaluate the contrasting effects of circuit training with and without upper and lower limb resistance training on paroxysmal nocturnal dyspnea, functional capacity and endurance on post-CABG patients.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 20, 2025
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 5, 2025
Actual (reported)August 20, 2025
Actual (reported)December 20, 2025
Actual (reported)March 16, 2026
Actual (reported)March 20, 2026
Actual (reported)Modified Medical Research Council (mMRC)
The mMRC Dyspnea Scale is a validated tool to assess the severity of dyspnea among the patients with pulmonary complications. This scale was utilized to quantify the symptoms of paroxysmal nocturnal dyspnea among the participants in the study, offering an insight to the effectiveness of exercise interventions on the respiratory symptoms
First day
1-Repetition Maximum (1-RM)
1-RM is a useful tool in the studies in the studies evaluating the effectiveness of strength training such as those addressing upper and lower limb resistance training. This test specifies the maximum weight that a subject can lift in a single repetition, providing a precise, quantitative baseline evaluation of dynamic strength. It can be used as a solid baseline for tracking and comparing strength changes during intervention. Thus, 1-RM is a practical and objective tool in rehabilitation research. It allows the researchers to analyze the effectiveness of certain treatments and monitor functional changes over the course of treatment or regimen.
First day
Modified Borg Scale (BORG CR-10):
Modified Borg Dyspnea Scale is a highly validated subjective tool, to assess rate of perceived exertion during exercise to monitor exercise intensity and tailor to individual patient in cardiac rehabilitation settings. It is safe and cost-effective. It has a rating of 0-10 with zero representing (no breathlessness) and 10 (maximal exertion). It is a subjective measure of how hard the body is pushing against exertion during exercise. Specially designed for the assessment of cardiac endurance
First day
A series of exercises in a circuit format with Resistance Training: for upper and lower limbs (30-40% of 1-RM)
Exercises in circuit format (30-40 minutes)
A series of exercises in a circuit format, with 1 minute of exercise followed by 30 seconds of rest. The circuit was repeated 2-3 times, with a 2-minute break between circuits along with upper and lower limb Resistance exercises (30-40% of 1-RM) using weights and therapeutic bands
A series of exercises in a circuit format, with 1 minute of exercise followed by 30 seconds of rest. The circuit was repeated 2-3 times, with a 2-minute break between circuits.
Punjab Institute of Cardiology
Lahore, Punjab Province, 54000, Pakistan
Qurat ul Ain, MS
Riphah International University
60 participants (actual enrollment reported by the registry).
First Submitted
March 16, 2026
First Posted
March 20, 2026
Study Start
July 5, 2025
Actual (reported)6-Minute Walk Test 6-MWT:
It is a reliable tool for assessing functional capacity among the patient population that present with underlying cardiovascular and pulmonary conditions. We used this tool in the assessment of functional capacity among the patients that participated in the study. This test specifically measures the distance covered in 6 minutes. In this test the participant walks along a flat straight pathway (usually 30-meter indoor corridors) in six minutes at their own pace. The maximum distance covered in 6 minutes documented the functional capacity among the participants under study.
First day
Incremental Shuttle Walk Test (ISWT)
Incremental Shuttle Walk Test (ISWT) is a highly reliable and valid tool for the assessment of cardiac endurance as a distinct outcome separately from overall functional capacity. It measures cardiac endurance under progressively increasing workloads within the safe limits. We used this tool to assess the cardiopulmonary endurance and baseline functional status in CABG population and to measure the improvements post-intervention outcomes. The test is safe, cost-effective and convenient to implement in all the clinical settings requiring little equipment and simultaneously assesses physiological responses such as heart-rate HR, oxygen saturation SPO2, and blood pressure in accordance with the subjective effort.
First day
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Primary Completion
August 20, 2025
Actual (reported)Study Completion
December 20, 2025
Actual (reported)Last Updated
March 20, 2026
Record last verified: 2026-03
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