NCT07484308

Brief Summary

The aim of this study is to evaluate the utility of URM technology in imaging renal microcirculatory blood flow in patients with renal failure, and to investigate its clinical feasibility for assessing renal function, disease staging and monitoring treatment response.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2024

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2025

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2026

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

March 16, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 20, 2026

Completed
Last Updated

March 20, 2026

Status Verified

March 1, 2026

Enrollment Period

1 year

First QC Date

March 16, 2026

Last Update Submit

March 16, 2026

Conditions

Kidney Failure

Keywords

URMKidney failure

Outcome Measures

Primary Outcomes (1)

  • Correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory renal function markers (eGFR, Scr)

    From enrollment to the end of treatment at 14 days

Study Arms (2)

Patients with acute kidney failure

EXPERIMENTAL
Diagnostic Test: Ultrasound super-resolution blood flow imaging

Patients with chronic kidney failure

EXPERIMENTAL
Diagnostic Test: Ultrasound super-resolution blood flow imaging

Interventions

Ultrasound super-resolution blood flow imagingDIAGNOSTIC_TEST

The primary objective is to examine the correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory markers of renal function (eGFR, Scr)

Also known as: Patients with acute kidney failure, Patients with chronic kidney failure
Patients with acute kidney failurePatients with chronic kidney failure

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province)

Jinan, Shandong, China

Location

MeSH Terms

Conditions

Renal Insufficiency

Condition Hierarchy (Ancestors)

Kidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Chief Physician

Study Record Dates

First Submitted

March 16, 2026

First Posted

March 20, 2026

Study Start

October 1, 2024

Primary Completion

October 1, 2025

Study Completion

March 1, 2026

Last Updated

March 20, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)